The present volume deals with drugs which play an important role in the
therapy of schizophrenia. It describes the introduction of the first
antipsychotics on the market and the importance of clozapine, a
prototype for atypical antipsychotics, for further investigation of
other potentially atypical antipsychotics, which may have an important
impact on the therapy and especially the well being of schizophrenic
patient
Reihe
Sprache
Verlagsort
Verlagsgruppe
Illustrationen
Dateigröße
ISBN-13
978-3-0348-8448-8 (9783034884488)
DOI
10.1007/978-3-0348-8448-8
Schweitzer Klassifikation
A general introduction.- to schizophrenia.- From first to second generation antipsychotics.- Animal models for schizophrenia: an introduction.- The preclinical evaluation of atypical antipsychotics.- Receptor profile of antipsychotics.- Regional selectivity of antipsychotic drugs.- Screening models for antipsychotic drugs.- Simulation models for schizophrenia.- The clinical evaluation of atypical antipsychotics.- Clozapine: the first atypical antipsychotic.- Dopamine receptor subtypes and schizophrenia: a clinical perspective.- Multireceptor atypical antipsychotic drugs.- New discoveries in the development of antipsychotics with novel mechanisms of action: beyond the atypical antipsychotics with serotonin dopamine antagonism.
