Located at the interface between blood and the brain, the blood-brain barrier is a dynamic permeability barrier formed by a continuous layer of specialized endothelial cells endowed with important permeability, transport, and regulatory functions that both protect the internal milieu of the brain and allow essential nutrients to be transported into
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978-1-4987-2706-8 (9781498727068)
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Morphological and Functional Properties of the Blood-Brain Barrier. The Human Cerebral Cortex Microvascular System: Development and Composition of the Meningeal and Intracerebral Extrinsic and Intrinsic (Blood-Brain Barrier) Compartments. Heterogeneity of the CNS Microvascular Endothelium. The Neurovascular Unit. The Elusive Multipotent Microvascular Pericyte. Fluid-Forming Function of the Choroid Plexus: What is the Role of Aquaporin-1? The Expression and Function of ABC Transporters at the Blood-Brain Barrier. The Blood-Brain Barrier and the Immune Privilege of the Central Nervous System. Inflammatory Mediators and the Blood-Brain Barrier. Endothelial Surface-Associated Molecules of Relevance to the Immune Function of the Blood-Brain Barrier. Chemokines as Mediators of Leukocyte Trafficking and Activation at the Blood-Brain Barrier. Leukocyte Entry into the Brain.
