Fertility Preservation

Section 1 Introduction: 1. The evolution of the assisted reproduction technologies; 2. The effect of chemotherapy on the human reproductive system; 3. The effect of radiotherapy on the human reproductive system; 4. The need for fertility preservation in cancer patients; Section 2 Reproductive biology and cryobiology: 5. Life and death in the germ line: apoptosis and the origins of DNA damage in human spermatozooa; 6. Principles of vitrification as a method of cryopreservation in reproductive biology and medicine; Section 3 Fertility preservation in cancer and non-cancer patients: 7. Fertility preservation in non-cancer patients; 8. Fertility preservation in women with ovarian endometrioma: from surgery to oocyte and ovarian tissue freezing; 9. Pediatric cancer therapy and fertility; 10. Breast cancer therapy and fertility; 11. Fertility preservation in young adults with gastrointestinal and hematological malignancies; Section 4 Fertility preservation strategies in the male: 12. Transplantation of cryopreserved spermatogonia; 13. Cryopreservation and grafting of immature testicular tissue; 14. Use of cryopreserved sperm and ART after chemotherapy or radiotherapy; Section 5 Fertility preservation strategies in the female: medical/surgical: 15. Use of GnRH analogs for prevention of chemotherapy-induced gonadotoxicity; 16. Ovarian transposition before radiotherapy Yaron Gill and Togas Tulandi; 17. Fertility-saving surgery for gynaecological cancers; 18. Results of conservative management of ovarian malignant tumours; Section 6 Fertility preservation strategies in the female: ART: 19. Embryo cryopreservation as a fertility preservation strategy; 20. Vitrification of human oocytes as a fertility preservation strategy; 21. Autotransplantation of cryopreserved ovarian tissue: techniques and results; 22. ART and oocyte donation in cancer survivors; Section 7 Ovarian cryopreservation and transplantation: 23. Ovarian cryopreservation and transplantation: overview; 24. Cryopreservation of ovarian tissue by vitrification: techniques and results; 25. Ovarian tissue cryopreservation; 26. Risk of transplanting malignant cells in cryopreserved ovarian tissue; 27. Whole ovary freezing and transplantation; Section 8 In-vitro follicle culture: 28. Molecular and cellular integrity of cultured follicles; 29. In-vitro growth of human oocytes; 30. Contributions of ovarian stromal cells to follicle culture; 31. In-vitro maturation of germinal vesicle oocytes; 32. Survival of primordial follicles: tips and tricks; Section 9 New research and technologies: 33. The artificial ovary; 34. Uterus transplantation: research and clinical possibilities; 35. Ovarian allotransplantation; 36. Allotransplantation of human ovarian tissue; 37. Predicting ovarian futures: the contribution of genetics; Section 10 Ethical, legal and religious issues: 38. Fertility preservation: ethical considerations; 39. Legal issues of fertility preservation; 40. Christian ethics in fertility preservation.