Protein Kinases in Drug Discovery

1. Transporter proteins and its implication in human diseasesRitika Kabra and Shailza Singh2. Protein kinase CK2 inhibition as a pharmacological strategyChristian Borgo and Maria Ruzzene3. Emerging role of protein kinases in diabetes mellitus: From mechanism to therapyPreeti Gupta, Aaliya Taiyab, and Md Imtaiyaz Hassan4. Dual roles of ATP-binding site in protein kinases: Orthosteric inhibition and allosteric regulationMingyu Li, Ashfaq Ur Rehman, Yaqin Liu, Kai Chen, and Shaoyong Lu5. Pseudokinases: Prospects for expanding the therapeutic targets armamentariumNayana Devang, Adyashree Pani, and G.K. Rajanikant6. Chemogenomics and bioinformatics approaches for prioritizing kinases as drug targets for neglected tropical diseasesJoyce Villa Verde Bastos Borba, Arthur Carvalho Silva, Marilia Nunes Nascimento Lima, Sabrina Silva Mendonca, Nicholas Furnham, Fabio Trindade Maranhão Costa, and Carolina Horta Andrade7. Targeting malaria protein kinasesG.C. Cassiano, T.A. Tavella, M.N. Nascimento, D.A. Rodrigues, P.V.L. Cravo, Carolina Horta Andrade, and Fabio Trindade Maranhão Costa8. Yeast-based high-throughput screens for discovery of kinase inhibitors for neglected diseasesT.A. Tavella, G.C. Cassiano, Fabio Trindade Maranhão Costa, P. Sunnerhagen, and E. Bilsland9. Structural studies of full-length receptor tyrosine kinases and their implications for drug designAdam Bajinting and Ho Leung Ng