Innate Immune System of Skin and Oral Mucosa

Preface ix
Contributors xi
Part I. Overview of Skin and Muscosal Innate Immunity:History, Ethics, and Science
Chapter 1. Germ Free: Hygiene History and ConsumingAntimicrobial and Antiseptic Products 3
Jennifer Tebbe-Grossman and Martha N. Gardner
Chapter 2. Ethical Responsibilities in Formulating, Marketing,and Using Antimicrobial Personal Products 43
Kenneth A. Richman
Chapter 3. Role of Stratum Corneum in Permeability BarrierFunction and Antimicrobial Defense 59
Peter M. Elias
Part II. Antimicrobial Lipids and Peptides
Chapter 4. Antimicrobial Lipids of the Skin and Oral Mucosa75
Kim A. Brogden, David R. Drake, Deborah V. Dawson, Jennifer R.Hill, Carol L. Bratt, and Philip W. Wertz
Chapter 5. Resident Microflora and Antimicrobial Peptides ofSkin 83
Shamim A. Ansari
Chapter 6. Defensins 109
Neelam Muizzudin
Chapter 7. Antimicrobial Peptides of Skin and Oral Mucosa117
Whasun O. Chung and Henrik Dommisch
Chapter 8. Vernix Caseosa and Innate Immunity 145
Steven B. Hoath, Vivek Narendran, and Marty O. Visscher
Part III. Host Cellular Components of Innate Immunity
Chapter 9. Sentinel Role of Mast Cells in Innate Immunity173
Zhenping Wang and Anna Di Nardo
Chapter 10. Cellular Immunity of the Skin: Langerhans Cells andDendritic Cells 195
Karen E. Burke and Niroshana Anandasabapathy
Part IV. Innate Immunity Response to Stress and Aging
Chapter 11. Changes in Skin Immunity with Age and Disease217
Barbara Geusens, Iles Mollet, Chris D. Anderson, Sarah Terras,Michael S. Roberts, and Jo Lambert
Chapter 12. Epidermis as a Sheild from Radiation and OxidativeStress 259
Giuseppe Valacchi
Chapter 13. The Impact of the Skin's Innate Immunity byCosmetic Products Applied to the Skin and Scalp 275
Rudranath Persaud and Thomas Re
Chapter 14. UV-Induced Immunosuppression of Skin 281
Roger L. McMullen
Part V. Innate Immunity Microbial Challenges
Chapter 15. Deranged Antimicrobial Barrier in Atopic Dermatitis:Roles of Sphingosine, Hexadecenoic Acid, and Beta-Defensine-2307
Gangi Imokawa
Chapter 16. Resident Microflora of the Skin and Oral Mucosa325
David R. Drake
Chapter 17. Corynebacterium Species and Their Role in theGeneration of Human Malodor 333
Carol L. Bratt and Nava Dayan
Index 351