Novel Platforms for Drug Delivery Applications covers diverse aspects in the design, synthesis and characterization of novel drug delivery platforms and devices. This book comprehensively details the development, application and performance of various novel molecular frameworks as potent drug delivery vehicles. Chapters cover a range of materials and molecular platforms for drug delivery, from hydrogels, nanocarriers and metal-organic-frameworks, to ¿-cyclodextrin and polyphosphazene. Each chapter discusses the benefits and limitations of each drug delivery system, as well as toxicological and safety implications. This book offers an interdisciplinary approach to this fast-moving topic, bridging the disciplines of materials science and pharmacology.
- Provides an up-to-date single resource on novel drug delivery platforms, a rapidly evolving field of research
- Covers a broad range of materials, systems and release mechanisms, including in vivo and in vitro studies
- Describes the synthesis, properties, formulation and application of various novel drug delivery systems
Reihe
Sprache
Verlagsort
Verlagsgruppe
Elsevier Science & Techn.
Illustrationen
Approx. 180 illustrations (80 in full color)
Dateigröße
ISBN-13
978-0-323-91378-2 (9780323913782)
Schweitzer Klassifikation
1. Introduction: state of the art, new challenges, and opportunities for drug delivery and its application2. Drug delivery application: an outlook on past and present technologies3. General mechanisms of drug loading and sustained release 4. Supramolecular hydrogels as drug delivery systems for nerve regeneration and wound healing5. Molecularly imprinted polymeric carriers for controlled drug release6. Engineered extracellular vesicles as drug delivery systems for the next generation of nanomedicine7. Polyelectrolyte multilayer films for cancer therapy8. Porous metal9. Stimulus-responsive liposomes as smart nanocarriers for drug delivery applications10. Hybrid platforms for drug delivery applications11. Self-nanoemulsifying drug delivery systems with bioavailability potential12. Graphene-based nanomaterials for targeted drug delivery and tissue engineering13. Bionanocomposites as a new platform for drug delivery systems14. Nanotube platforms for effective drug delivery applications15. Biodegradable polymeric nanoparticle drug for oral delivery applications16. Delivery of radiopharmaceuticals and theranostic agents: targeted alpha therapy17. Controlled drug release and drug delivery applications from mesoporous nanoparticles18. Porous nanostructured metal oxides as potential scaffolds for drug delivery19. Thin films as an emerging platform for drug delivery20. Modeling and simulation in drug delivery21. In-vivo drug release studies22. Toxicity measurement and toxicity studies of drug delivery23. Nasal and pulmonary routes of drug delivery24. "Gene therapy: ethical and regulatory issues25. New challenges in drug discovery
