Gastroesophageal reflux (GER) refers to symptoms and events that result from abnormal regurgitation of gastric contents into the esophagus. GER is a common clinical problem that affects large segments of the general population. The spectrum of problems associated with GER is now known to also involve extra-esophageal sites. Respiratory diseases, in particular bronchial asthma, can be exacerbated by multiple triggers, including GER. The relationship between the occurrence of gastroesophageal disorders and changes in respiratory function has been known for over a century, but the mechanism by which intraesophageal acid regurgitation can produce respiratory symptoms is still debated. The reasons for these concurrent pathological events are also not fully understood. Determining, for instance, whether reflux itself initiates or exacerbates asthma, or whether asthma or its treatment primarily causes GER is a matter of current investigation.
Sprache
Verlagsort
Verlagsgruppe
Illustrationen
42 s/w Abbildungen
VIII, 200 p. 42 illus.
Dateigröße
ISBN-13
978-88-470-2147-1 (9788847021471)
DOI
10.1007/978-88-470-2147-1
Schweitzer Klassifikation
Gastroesophageal Reflux in Gastroenterology.- Epidemiology of Gastroesophageal Reflux.- Pathophysiology of Gastroesophageal Reflux.- Gastroesophageal Reflux in Pneumology.- Pathophysiological Determinants of Gastroesophageal Reflux, and the Role of Esophageal and Airway Receptors.- The Role of Protons in the Activation of Primary Sensory Neurons.- An Ovine Model of GERD-Induced Bronchoconstriction.- Clinical Signs of Gastroesophageal Reflux.- Epidemiology of Gastroesophageal Reflux in Asthma.- Gastroesophageal Reflux and Nonspecific Hyperreactivity of Upper Aerodigestive Tract: Possible Correlations with Otorhinolaryngological Disorders.- Bronchial Asthma and GER.- Gastroesophageal Reflux in Chronic Obstructive Pulmonary Disease.- Gastroesophageal Reflux and Interstitial Lung Disease.- Diagnostic Techniques for Gastroesophageal Reflux Detection.- Imaging of Gastroesophageal Reflux.- The Esophageal Scintiscan.- Ambulatory Esophageal pH Monitoring in the Diagnosis of Gastroesophageal Reflux.- Diagnostic Techniques for Assessing Pulmonary Involvement.- Lung Function and Bronchial Hyperreactivity.- Fiberoptic Bronchoscopy and Bronchoalveolar Lavage in the Management of Children with Gastroesophageal Reflux.- Therapy.- Therapy of Gastroesophageal Reflux Disease: The Gastroenterological Approach.- The Role of Respiratory Drugs in Gastroesophageal Reflux.
