This detailed volume focuses on recent technological, computational, and biostatistical advances in the field of high-throughput metabolomics. Chapters encompass methods, platforms, and analytical strategies for steady state measurements and metabolic flux analysis with stable isotope-labeled tracers, in biological matrices of clinical relevance and model organisms. Mass spectrometry-based or orthogonal methods are discussed, along with computational and statistical methods to address data sparsity in high-throughput metabolomics approaches. As a part of the highly successful
Methods in Molecular Biology
series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and practical,
High-Throughput Metabolomics: Methods and Protocols
provides tools that can bring about thenext generation of clinical biochemistry in a cost-effective, rigorous fashion, exponentially advancing our capacity to investigate nature while hastening the advent of personalized medicine.
Reihe
Sprache
Verlagsort
Verlagsgruppe
Illustrationen
63
20 s/w Abbildungen, 63 farbige Abbildungen
XV, 459 p. 83 illus., 63 illus. in color.
Dateigröße
ISBN-13
978-1-4939-9236-2 (9781493992362)
DOI
10.1007/978-1-4939-9236-2
Schweitzer Klassifikation
