Over the last quarter century or so, specialization within obstetrics and gynecology, and pediatrics has resulted in the development of the disciplines of maternal-fetal medicine and neonatology, respectively. A primary focus of maternal-fetal medicine has been to understand the mechanism(s) of premature delivery and develop treatment modalities for improving the length of gestation. A primary focus of neonatology has been to under stand the causes of respiratory distress in the neonate. Success has resulted, not only in the lengthening of gestation, but an improved understanding of the causes and treatment of neonatal respiratory disease. With increasing success has come the necessity to under stand the metabolic principles of the parturient, the fetal/placenta unit, and the neonate. These principles are clearly very important from multiple aspects. Increased understand ing of metabolism of the pregnant woman would explain the aberrations occurring in normal and abnormal pregnancy and improve nutritional support for the parturient. A prime example of altered metabolism is the parturient with diabetes. Understanding metabolism ofthe fetal/placenta unit is necessary to increase the probability that the fetus will be born appropriate for size irrespective of the gestational age. The various compo nents of neonatal metabolism are important, not only for understanding the changes in physiology and biochemistry occurring in the developing neonate, but the principles by which nutritional support should be provided.
Rezensionen / Stimmen
From reviews of the critically acclaimed first edition:
"an incredible amount of information...of utmost value not only to the basic investigator but also to the clinician." - JAMA
"a first-rate reference textbook that should be on the shelves of every institution that provides care for the pregnant women or her children" - NEJM
"I know of no other volume in which these important topics are integrated into a single text...I enthusiastically recommend it as a valuable reference to researchers, clinicians, fellows, and students." - TEM
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ISBN-13
978-1-4684-0400-5 (9781468404005)
DOI
10.1007/978-1-4684-0400-5
Schweitzer Klassifikation
Section I: General Principles of Metabolism.- 1 Methodology for the Study of Metabolism: Kinetic Techniques.- 2 Methodology for the Study of Metabolism: Cellular and Molecular Techniques.- 3 Methodology for the Study of Metabolism: Animal Models.- 4 Control of Metabolism in the Normal Adult.- 5 Insulin: Biochemical and Physiological Aspects.- 6 Contrainsulin Hormones: Biochemical and Physiological Aspects.- 7 Somatomedins: Biochemical and Physiological Aspects.- Section II: Maternal Metabolism During Pregnancy.- 8 Glucose Metabolism in Pregnancy.- 9 Protein Metabolism in Pregnancy.- 10 Lipid Metabolism in Pregnancy.- 11 Prostaglandins in Pregnancy.- 12 Energy Metabolism in Pregnancy.- 13 Exercise in Pregnancy: Effects on Metabolism.- Section III: Fetal-Placental Metabolism.- 14 Glucose Metabolism in the Fetal-Placental Unit.- 15 Protein Metabolism in the Fetal-Placental Unit.- 16 Lipid Metabolism in the Fetal-Placental Unit.- 17 Respiration in the Fetal-Placental Unit.- 18 Circulation in the Fetal-Placental Unit.- 19 Water Metabolism in the Fetal-Placental Unit.- Section IV: Neonatal Metabolism.- 20 Neonatal Glucose Metabolism.- 21 Inborn Errors of Carbohydrate Metabolism.- 22 Neonatal Protein Metabolism.- 23 Inborn Errors of Amino Acid and Organic Acid Metabolism.- 24 Neonatal Lipid Metabolism.- 25 Neonatal Carnitine Metabolism.- 26 Neonatal Mineral Metabolism.- 27 Neonatal Trace Element Metabolism.- 28 Neonatal Vitamin Metabolism-Fat Soluble.- 29 Neonatal Vitamin Metabolism-Water Soluble.- 30 Neonatal Energy Metabolism.- 31 Neonatal Thermoregulation.- 32 Neonatal Water Metabolism.- 33 Body Composition of the Neonate.- 34 Small for Gestational Age Neonate.- 35 Infant of the Diabetic Mother.- 36 Metabolism of the Neonate Requiring Surgery.- 37 Nutritional Support ofthe Neonate: Alternate Fuels and Routes of Administration.