High-Density Lipoproteins as Biomarkers and Therapeutic Tools

Chapter 1. Improvement of HDL.- 1-1.Clinical application of HDL: Overview.- 1-2.Regression effect of V156K-apoA-I.- 1-3.Anti-diabetic effect of V156K-apoA-I.- 1-4.Vitamin C and HDL.- 1-5.Growth hormone-1 in HDL.- 1-6.Growth hormone-2 in HDL.- 1-7.Omega-3 and HDL.- Chapter 2. HDL as therapeutic tools.- 2-1.Delivery vehicle for therapeutics : Overview.- 2-2.Gene delivery: adenovirus and V156K-apoA-I.- 2-3.Solubilization of rapamycin and delivery.- 2-4.Solubilization of minoxidil and delivery.- Chapter 3. Enhancement of HDL by policosanol: anti-aging and longevity.- 3-1.Policosanol and HDL functionality.- 3-2.Policosanol and raising HDL in zebrafish.- 3-3.Policosanol and CETP inhibition: human trial 8 weeks.- 3-4.Policosanol and blood pressure lowering: human trial 8 weeks.- 3-5.Policosanol blood pressure lowering human trial for 24 weeks.- 3-6.Policosanol and improvement of aortic stiffness.- 3-7.Policosanol and blood pressure lowering in rat model.- 3-8.Twelve week consumption of policosanol and lowering blood pressure.- 3-9.Publication analysis of policosanol-related studies.- 3-10.Athero-protective effects of policosanol and sugar cane wax acid.- 3-11.Cuban sugarcane wax acids and policosanol improved serum lipid profiles.- Summary and perspectives.- Epilogue.