Textbook of Arterial Stiffness and Pulsatile Hemodynamics in Health and Disease, Two Volume Set covers the principles, physiology, biologic pathways, clinical implications and therapeutics surrounding arterial stiffness and pulsatile hemodynamics, along with a thorough overview of the field. The book presents complex engineering concepts in a way that those in science and medicine can more easily understand. It includes detailed illustrations. Additionally, it presents advanced bioengineering concepts in boxes for readers who wants more in-depth biophysical knowledge. This is a must-have reference for students, researchers and clinicians interested in learning more about this field.
- Incorporates case studies and calculations/worked examples with mathematical principles explained in a conceptual manner without complicated formulas
- Features chapter contributions from leading international researchers and clinicians
- Covers principles, physiology, biologic pathways, clinical implications and therapeutics
Sprache
Verlagsort
Verlagsgruppe
Elsevier Science & Techn.
Illustrationen
Approx. 250 illustrations (125 in full color)
Dateigröße
ISBN-13
978-0-323-91648-6 (9780323916486)
Schweitzer Klassifikation
Section I. Biophysical and Technical Principles1. Basic Principles of pulsatile pressure and flow phenomena in elastic vessels2. Measurements of arterial pressure and flow in vivo3. Essential Principles of Pulsatile Pressure-flow relations in the arterial tree4. Magnetic Resonance Imaging for the assessment of aortic stiffness and pulsatile hemodynamics5. Computed tomography of the aorta6. Radionuclide-based Imaging of the aortic wall7. Arterial wall stiffness: basic principles and methods of measurement in vivo8. Ambulatory measurements of pulsatile hemodynamics9. Animal Models and Ex-vivo Methods to Study Arterial Stiffness
Section II. Basic and Applied Physiology10. Hemodynamic role of the Aorta11. Wave Reflections in the arterial tree12. Linking Arterial Stiffness to Microvascular Remodeling13. Myocardial function: from myofilaments to cardiac pump14. Systolic-diastolic coupling15. Ventricular-arterial coupling: The pressure-volume plane16. Myocardial wall stress and the systolic loading sequence17. Assessment of Ventricular Arterial Interactions via arterial pressure-flow relations in humans18. Hemodynamic Determinants of Myocardial Oxygen Demand and Supply
Section III. Biologic pathways leading to arterial stiffness and dysfunctional pulsatile hemodynamics19. Role of elastin and elastin-derived peptides in arterial stiffness: from synthesis to potential therapeutic interventions20. Inflammation and arterial stiffness21. Mechanisms of Aortic Wall Calcification22. Vascular smooth muscle dysfunction and arterial stiffness23. Endothelial cell dysfunction and Senescence: Biologic mechanisms and Hemodynamic consequences24. Autonomic and neuroendocrine modulation of arterial stiffness and hemodynamics25. Cellular mechanisms of ageing and their impact on the aortic/arterial wall
SECTION IV. Clinical significance of arterial stiffness and pulsatile hemodynamics26. Normal Aging: Arterial Stiffness and remodeling over the life course27. Early Vascular Aging and Supernormal Vascular Aging: Genetics, Epigenetics, and Environment28. Ethnic differences in arterial stiffness and central aortic hemodynamics29. Arterial Stiffness and Pulsatile hemodynamics in Systemic Hypertension30. Arterial Stiffness and Pulsatile hemodynamics in Diabetes and Obesity31. Cardiovascular Risk Prevention in Clinical Practice: Current Guidelines in the USA and Europe32. Cardiovascular Risk Prevention in Clinical Practice: Current Guidelines in Asia33. Arterial Stiffness, Cardiovascular Risk and Strategies for enhancing risk Stratification34. Role of the arterial tree in Physiologic Adaptations to exercise35. Invasive Hemodynamic Assessments during exercise: Normal patterns and clinical value36. Arterial Stiffness and Pulsatile hemodynamics in Heart Failure with Reduced and Preserved Ejection Fraction37. Ventricular-Arterial Coupling and Arterial Load in Aortic Valvular Disease38. Arterial Stiffness and Atherosclerosis: Mechanistic and Pathophysiologic Interactions39. Arterial Stiffness and Pulsatile hemodynamics in Coronary Artery Disease and other forms of Atherosclerotic vascular diseases40. Arterial Stiffness and Pulsatile hemodynamics in Renal disease41. Arterial Stiffness, Pulsatile hemodynamics, Cognitive dysfunction42. Arterial Stiffness and Pulsatile hemodynamics in pregnancy and pregnancy-related vascular complications 43. Arterial Stiffness and Pulsatile Hemodynamics in Pediatric populations44. Aortopathies and Arteriopathies45. Pulsatile hemodynamics and arterial stiffness in primary aortopathies46. Arterial Hemodynamics and Pulsatile Hemodynamics in Congenital Heart Disease47. Arterial Stiffness and Pulsatile Hemodynamics in Acute and Chronic Infectious Diseases48. Arterial Stiffness, Hemodynamics and Microvascular Complications in conditions characterized by low arterial pulsatility
SECTION V. Therapeutic approaches to improve arterial stiffness and pulsatile hemodynamics49.
