The Cerebral Cortex in Neurodegenerative and Neuropsychiatric Disorders: Experimental Approaches to Clinical Issues focuses on how pre-clinical investigations are addressing the clinical issues surrounding the involvement of the cerebral cortex in selected conditions of the nervous system, including Alzheimer's Disease, Parkinson's, addiction, and cardiovascular dysregulation.
Each chapter is written by an expert in his/her field who provides a comprehensive review of the clinical manifestations of cortical involvement and experimental techniques currently available to tackle cortical issues in disease. Thus, this present title provides a link between cortical clinical problems and investigational approaches to help foster future research with high translational value.
- Offers a comprehensive overview on the best available in vivo and in vitro models to study cortical involvement
- Presents models and specific techniques that help to guide investigators in their choices on how to address research questions experimentally
- Provides expert commentary and a perspective on future trends at the end of each chapter
- Addresses translational advances and promising therapeutic options
- Includes references to key articles for additional detailed study
Sprache
Verlagsort
Verlagsgruppe
Elsevier Science & Techn.
ISBN-13
978-0-12-801956-6 (9780128019566)
Schweitzer Klassifikation
Part I. Introductory Chapters
Chapter 1. Anatomy of the Cerebral Cortex
Chapter 2. Cortical Plasticity in Response to Injury and Disease
Chapter 3. Imaging Approaches to Cerebral Cortex Pathology
Part II. The Cerebral Cortex in Neurodegenerative Disorders
Chapter 4. Alzheimer's Disease
Chapter 5. Vascular Dementia
Chapter 6. Frontotemporal Dementia
Chapter 7. Parkinson's Disease and the Cerebral Cortex
Chapter 8. Huntington Disease
Chapter 9. Cortical Manifestations in Amyotrophic Lateral Sclerosis
Chapter 10. Cortical Involvement in Multiple Sclerosis
Part III. The Cerebral Cortex in Neuropsychiatric Disorders
Chapter 11. Prefrontal Cortical Abnormalities in Cognitive Deficits of Schizophrenia
Chapter 12. Role of the Prefrontal Cortex in Addictive Disorders