This book examines current knowledge and recent advances in the study of fundamental processes involved in neuronal death, particularly oxidative stress as a causal agent or risk factor. The author presents discussion of oxidative stress in neuronal apoptosis and its role in the neuropathogenesis of age-related neurodegenerative diseases exemplified by Alzheimer's disease, Parkinson's disease and Amyotrophic Lateral Sclerosis.
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ISBN-13
978-3-662-22516-5 (9783662225165)
DOI
10.1007/978-3-662-22516-5
Schweitzer Klassifikation
1. Introduction.- 2. Biology of Oxidative Stress.- 3. Oxidative Stress in Neuronal Death and Apoptosis.- 4. Oxidative Stress, Cerebral Aging and Longevity.- 5. Oxidative Stress in Alzheimer's Disease.- 6. Oxidative Stress in Down's Syndrome.- 7. Oxidative Stress in Amyotrophic Lateral Sclerosis.- 8. Oxidative Stress in Parkinson's Disease.- 9. Conclusions.
