Human Aging: From Cellular Mechanisms to Therapeutic Strategies offers an exhaustive picture of all the biological aspects of human aging by describing the key mechanisms associated with human aging and covering events that could disrupt the normal course of aging. Each chapter includes a summary of the salient points covered, along with futures prospects. The book provides readers with the information they need to gain or deepen the skills needed to evaluate the mechanisms of aging and age-related diseases and to monitor the effectiveness of therapies aimed at slowing aging.
The book encourages PhD and Postdoc students, researchers, health professionals and others interested in the biology of aging to explore the fascinating and challenging questions about why and how we age as well as what can and cannot be done about it.
- Concentrates on different processes, e.g., oxidative stress, cellular senescence and Inflammaging
- Offers the ability to access cross-sectional knowledge more easily
- Written by expert researchers in biogerontology who are actively involved in various fields within aging research
Sprache
Verlagsort
Verlagsgruppe
Elsevier Science & Techn.
Illustrationen
Approx. 100 illustrations (25 in full color)
Dateigröße
ISBN-13
978-0-12-822737-4 (9780128227374)
Schweitzer Klassifikation
1. Aging and longevity: An evolutionary approach2. Demographic aspects of aging3. Pathobiology of aging: An introduction to age-related diseases4. Cellular senescence and senescence-associated secretory phenotype (SASP) in aging process5. The role of inflammaging in the development of chronic diseases of older people6. A new perspective on ROS in aging with an integrated view of the gut microbiota7. Aging of immune system8. Vaccination in old age: Challenges and promises9. Resilience signaling and hormesis in brain health and disease10. Different components of frailty in the aging subjects-The role of sarcopenia11. Hormones in aging12. Chronobiology and chrononutrition: Relevance for aging13. Nutraceutical approach to age-related diseases-The clinical evidence on cognitive decline14. Ways to become old: Role of lifestyle in modulation of the hallmarks of aging15. Nutritional biomarkers in aging research16. The role of cytomegalovirus in organismal and immune aging17. Ethics of aging18. Conclusions. Slowing aging and fighting age-related diseases, from bench to bedside?
