Menopause

Part I: Biological Background.- 1. Menopause, a stage in the life of women.- 2. Menopause: the concepts and the biological background.- 3. Premature Ovarian Insufficiency.- Part II: Impact of Estrogen Depletion on Symptoms and Quality of Life.- 4. Clinical Symptoms and Quality of Life: Vasomotor Symptoms and Mood.- 5. Clinical symptoms and quality of life: insomnia and muscle/joint aches.- 6. Genitourinary Syndrome of the Menopause. Vaginal health and microbiota.- 7. Sexual Health.- Part III: The Impact of Estrogen Depletion on Disease Susceptibility.- 8. Postmenopausal osteoporosis.- 9. The metabolic syndrome during female midlife and beyond.- 10. The impact of estrogen decline on other noncommunicable diseases.- Part IV: Management of Menopause.- 11. Hormone therapy (I): Estrogens, progestogens and androgens.- 12. Hormone Therapy (II): Tibolone and The TSEC Concept.- 13. The effect of Menopause Hormone Therapy on climacteric symptoms.- 14. The impact of hormone therapy on other noncommunicable diseases. Central nervous system, cardiovascular tree, osteoarthritis and cancer.- 15. Non-hormonal management of the menopause.- 16. Complementary and alternative therapies for vasomotor symptoms during climacteric and beyond.- 17. Lifestyle: physical activity.- 18. Nutritional management of menopausal women.- Part V: Menopause in the Context of Healthy Ageing.- 19. Frailty and comorbidities. Frailty in women.- 20. Muscle strength, dynapenia, and sarcopenia during female midlife and beyond.- 21. Empowerment of women and lifestyle. The help of digital technologies.