Bone Marrow and Bone Tissue

The clinical significance of histopathology of marrow-containing bone.- a) From a viewpoint of practical diagnosis.- b) From a scientific viewpoint.- Technical requirements of histobiopsy of marrow-containing bone.- a) Biopsy (myelotomy).- b) Histologic preparation.- c) Microtomy.- d) Staining.- e) Microscopy.- Indications for histobiopsy (myelotomy) of marrow-containing bone.- General histomorphology and pathology.- a) Preliminary remarks to histogenesis, morphogenesis, topography and physiology.- b) Normal values.- Illustrations Preliminary remarks.- I. General histopathology of bone marrow and bone.- Cancellous bone of the iliac crest - Normal and abnormal structure.- Structural elements of normal bone growth.- Vascularization of bone and marrow.- Pathological changes of blood vessels.- Thrombosis.- Reticular parenchyma and interstices.- Giant cells of bone marrow.- II. Special histopathology of bone marrow and bone.- Panmyelopathy: acute and subacute myelitis.- Panmyelopathy: subacute and chronic myelitis.- Panmyelopathy: hyperergic myelitis in rheumatoid arthritis..- Panmyelopathy: hyperergic myelitis.- Panmyelopathy: nephrogenic myelopathy.- Panmyelopathy: hepatogenic myelopathy.- Other panmyelopathies.- Granulomatous myelitis.- Pathological erythropoiesis.- Pathological thrombopoiesis.- Combined disorders of myelopoiesis.- Differentiated myeloid haemoblastoses.- The syndrome of myelofibrosis and ostemyelosclerosis.- Myelofibrosis and osteomyelosclerosis during therapy.- Undifferentiated myeloid haemoblastoses.- Differentiated lymphatic haemoblastoses.- Lymphatic and lymphoreticular neoplasias.- Plasmocytoma.- Hodgkin's disease.- Reticular neoplasia.- Osteopathies.- Tumour metastases.