Cholesterol

Part 1. Cholesterol Chemistry and Cell Function 1. Cholesterol chemistry, and laboratory synthesisHélio M.T. Albuquerque, Clementina M.M. Santos, and Artur M.S. Silva 2. Molecular evolution of cholesterol and other higher sterols in relation to membrane structureOle G. Mouritsen 3. Role of cholesterol in maintaining the physical properties of the plasma membraneWitold K. Subczynski, Marta Pasenkiewicz-Gierula, Justyna Widomska, and Natalia Stein 4. The fundamental interaction of cholesterol with lipid membranes: The umbrella modelJuyang Huang 5. Model peptides and cholesterolIstván P. Sugár and Parkson Lee-Gau Chong 6. Cholesterol and ceramide: An unlikely pairAritz B. García-Arribas, Alicia Alonso, and Félix M. Goñi 7. Cholesterol-recognizing amino acid consensus motifs in transmembrane proteins: Comparative analysis of in silico studies and structural dataFodil Azzaz, Henri Chahinian, Nouara Yahi, Coralie Di Scala, Carlos J. Baier, Francisco J. Barrantes, and Jacques Fantini 8. Effects of cholesterol on the GPCR AT1 receptor and its interplay with AT1 antagonistsS. Kiriakidi, Z. Cournia, and T. Mavromoustakos 9. Principles of cholesterol regulation of ion channelsQiu-Xing Jiang and Irena Levitan 10. Fluorescent probes for microscopy visualization of cholesterol topography and dynamics in membranesFrancisco J. Barrantes 11. Cholesterol transport in blood, lipoproteins, and cholesterol metabolismMark T Mc Auley and Amy E Morgan 12. Common laboratory research methods for detection and quantification of cholesterolAnna N. Bukiya, Hanxuan Li, Steven Mysiewicz, and Wei Li Part 2. Cholesterol Homeostasis and its disruption 14. Diet-induced hypercholesterolemia in small laboratory animal modelsTina Herfel 15. Nutrition and cholesterol metabolismGhada A. Soliman 16. Cholesterol and early developmentIsabella Ellinger and Waranya Chatuphonprasert 17. Clinical and biochemical diagnostic methods: What do blood lipid levels tell us?Marshall B. Elam 18. Familial hypobetalipoproteinemia and abetalipoproteinemiaFrancine K. Welty 19. Critical illness and cholesterol levelsZdenek Zadak 20. Familial hypercholesterolemiaShifa Jebari-Benslaiman, Unai Galicia-Garcia, Asier Larrea-Sebal, Kepa B. Uribe, Cesar Martin, and Asier Benito-Vicente 21. Niemann-Pic type C disease (NPC)Agnieszka Lugowska 22. Rare monogenic disorders of cholesterol metabolismMalgorzata Bednarska-Makaruk and Agnieszka Lugowska 23. Secondary (acquired) hypercholesterolemiaArrigo F.G. Cicero and Ivan R. Cincione 24. Blood lipids and molecular pathways of atherogenesisRicardo Stein, Filipe Ferrari, and Vítor M. Martins 25. Lysosomal acid lipase: Roles in rare deficiency diseases, myeloid cell biology, innate immunity, and common neutral lipid diseasesGregory A. Grabowski and Hong Du 26. Cholesterol and pathogensTatiana M. Clemente and Stacey D. Gilk 27. Involvement of cholesterol and ß-amyloid in the initiation and progression of Alzheimer's diseaseLuis G. Aguayo, Jorge P. Roa, Carlos F. Burgos, and Juliana Gonzalez-Sanmiguel 28. Cholesterol and alcoholAndrew S. Bell, Emma M. O'Connell, and Falk W. Lohoff Part 3. Pharmacological Considerations and Perspectives 29. Cholesterol stiffening of lipid membranes and drug interactions: Insights from neutron spin echo and deuterium NMR spectroscopySudipta Gupta, Fathima T. Doole, Teshani Kumarage, Milka Doktorova, George Khelashvili, Rana Ashkar, and Michael F. Brown 30. Cholesterol in drug delivery systemsDanRong Hu and ZhiYong Qian 31. Modification of vascular receptor pharmacology by cholesterol: From molecular determinants to impact on arterial functionAlex M. Dopico, Anna N. Bukiya, and Kelsey C. North 32. Clinical strategies for reducing cholesterol levelsClaude K. Lardinois and Samantha Karr 33. Medicinal chemistry and pharmacology of statinsBob M. Moore, II and George A. Cook 34. Cyclodextrins as promising therapeutics against cholesterol overload Florina Zakany, Tamas Kovacs, Lajos Szente, and Zoltan Varga 35.