1 Antibiotics associated with Clostridium difficile mediated diarrhoea and/or colitis.- 2 Spectrum of disease.- 3 Diagnosis and treatment of antimicrobial agent-associated diarrhea and colitis.- 4 Detection, isolation and identification of Clostridium difficile.- 5 Detection of Clostridium difficile toxins.- 6 Epidemiology of antimicrobial agent-associated diarrhea and colitis.- 7 Typing Clostridium difficile.- 8 Clostridium difficile and colonization resistance.- 9 Characteristics of the toxins of Clostridium difficile.- 10 Interaction of Clostridium difficile toxin B (cytotoxin) with cultured cells.- 11 Animal models of Clostridium difficile infection.- 12 The pathology of antibiotic-associated colitis.- Concluding remarks The unanswered questions.- Reference section.
