Manual for Night-Time Emergencies for Pediatric Hematology-Oncology Fellows

Preface. List of contributors. Acknowledgments. List of abbreviations

I. Oncology

1. High White Blood Cell (WBC) Count. 2. Mediastinal Mass/ Superior Vena Cava (SVC) Syndrome. 3. Spinal/Paraspinal Mass. 4. Massive Hepatomegaly. 5. Tumor Lysis Syndrome (TLS)/Metabolic Abnormalities. 6. Differentiation Syndrome or Retinoic Acid Syndrome. 7. Fever in High-Risk Populations. 8. Typhlitis. 9. Methotrexate Toxicity. 10. Posterior Reversible Encephalopathy Syndrome (PRES).

II. Hematology

11. Severe Anemia. 12. Hemolytic Anemia. 13. Thrombotic Microangiopathy (TMA). 14. Transfusion Emergencies. 15. Sickle Cell Emergencies. 16. ACS in SCD. 17. Aplastic crisis in SCD. 18. Hemolytic crisis in SCD. 19. Pain/Vascoocclusive crisis. 20. Priapism in SCD. 21. Splenic sequestration. 22. Stroke/TIA in SCD. 23. Deep Venous Thrombosis (DVT)/Central Venous Thrombosis. 24. Pulmonary Embolus (PE). 25. Arterial Thrombosis. 26. Arterial (Acute Ischemic) Stroke. 27. Heparin-Induced Thrombocytopenia (HIT). 28. Bleeding Emergencies. 29. Thrombocytopenia with/without Bleeding. 30. Hemophilia. 31. Von Willebrand Disease. 32. Vitamin K Deficiency. 33. Other Factor Deficiencies. 34. Neonatal Hematologic Emergencies. 35. Covid and Hematologic Emergencies. 36. Hemophagocytic Lympho-Histiocytosis (HLH).

III. Vascular Anomalies

37. Pain . 38. Cellulitis vs inflammation. 39. Effusions with/without organ failure. 40. Pulmonary Embolus in vascular anomalies. 41. Kasabach-Merritt Phenomenon.

IV. General

42. Managing Symptoms at the End of Life. 43. What to do when a patient dies. 44. What ChatGPT says: Postscript.

Index.