Part I - Foundations of Neuroinfection1. Anatomical Organization of central nervous system (CNS)2. The enteric nervous system's (ENS) impact on the neurobiology of infectious diseases3. The role of the microbiota-gut-brain axis on the neurobiology of infectious diseases4. The role and function of specialized blood-neuronal barriers: Blood-CSF, blood-retinal, blood-spinal cord, blood-labyrinth, blood-nerve barriers, and blood-brain barrier (BBB)5. Neuroimmune interactions in the neurobiology of infectious diseases6. The routes and mechanisms of microbial translocation to the central nervous systemPart II - Bacterial Infections Of CNS7. Brain infections, encephalitis, and meningitis: Streptococcus pneumoniae8. Brain infections, encephalitis, and meningitis: Neisseria meningitidis9. Brain infections, encephalitis, and meningitis: Streptococcus agalactiae10. Brain infections, encephalitis, and meningitis: Mycobacterium tuberculosis11. Neurosyphilis12. Brain infections, encephalitis, and meningitis: Lyme disease - Lyme borreliosis13. Brain infections, encephalitis, and meningitis: Brucelosis14. Brain infections, encephalitis, and meningitis: Listeria monocytogenesis - Listeriosis15. Sepsis-associated encephalopathy: Understanding the brain dysfunction in sepsisPart III - Parasitic Infections Of CNS16. African trypanosomiasis: Comprehending the parasite pathogenesis in the brain17. Cerebral malaria: Understanding the parasite pathogenesis in the brain18. Neurocysticercosis19. Free-living amoebae: Pathogens and the central nervous system (CNS) disease20. Pathophysiological mechanisms of Toxoplasma gondii infection in the central nervous system (CNS)Part IV - Virus Infections Of CNS21. HIV-infected human brain: Implications in HIV infection and immune response22. SARS-CoV-2 and nervous system: From pathogenesis of disease to clinical manifestations23. The neurobiology of herpes simplex virus infection24. Zika virus: Infection of the central nervous system (CNS)25. Dengue fever and its neurological complications26. Japanese encephalitis27. West Nile viruses: Infection of the central nervous system (CNS)28. Tick-borne encephalitis (TBE)29. Chikungunya virus: Infection of the central nervous systemPart V- Fungal Infections Of CNS30. Brain infections, encephalitis, and meningitis: Cryptococcus sp.31. Central nervous system infection due to Histoplasma capsulatum32. Brain infections, encephalitis, and meningitis: Coccidioides sp.33. Brain infections, encephalitis, and meningitis: Candida sp.Part VI - Proteins and other peripheral mediators that affect the CNS34. Overview of human transmissible spongiform encephalopathies35. Prion-like proteins in health and disease36. Autoimmune encephalitis37. Encephalitis: from mechanisms to management