Mass Spectrometry of Nucleosides and Nucleic Acids

Overview of Recent Developments in the Mass Spectrometry of Nucleic Acid and Constituents. Mass Spectrometric Analysis of Deoxyinosines. Tandem Mass Spectrometry of Nucleic Acids. Mass Spectrometric Application in the Study of Cyclic Nucleotides in Biochemical Signal Transduction. Analysis of Urinary Modified Nucleosides by Mass Spectrometry. Mass Spectrometric Determination of DNA Adducts in Human Carcinogenesis. Sequence Distribution of Nucleobase Adducts Studied by Isotope Labeling of DNA-Mass Spectrometry. Electrospray Mass Spectrometry of Noncovalent Complexes between Small Molecule Ligands and Nucleic Acids. Electrospray Ionization-Mass Spectrometry for the Investigation of Protein-Nucleic Acid Interactions. Characterization of Noncovalent Complexes of Nucleic Acids with Peptides and Proteins by Mass Spectrometry. MALDI-TOF Detection of Specific Noncovalent Complexes of Highly Acidic Biomolecules with Pyrenemethylguanidinium. Quantitative Identifi cation of Nucleic Acids via Signature Digestion Products Detected Using Mass Spectrometry. Electrospray Ionization Mass Spectrometry for the Direct Analysis of Modified Nucleosides in Small RNAs. LC-MS/MS for the Examination of the Cytotoxic and Mutagenic Properties of DNA Lesions. Influence of Metal Ions on the Structure and Reactivity of Nucleic Acids. Index.