This volume presents valuable techniques for studying the class of ligand-activated transcription factors known as nuclear receptors. After a brief overview of the history of the field, chapters cover methods to detect the receptors and their mRNAs in various tissues, protocols to characterize nuclear receptor modulators and activities, their signaling and roles in certain pathogenesis, molecular modeling of nuclear receptor-ligand interactions, as well as the utility of informatics in the field of nuclear receptors. Written in the highly successful
Methods in Molecular Biology
series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and cutting-edge,
Nuclear Receptors: Methods and Experimental Protocols
seeks to aid researchers working toward furthering ourunderstanding of these vital receptors and their role in numerous pathological conditions.
Reihe
Sprache
Verlagsort
Verlagsgruppe
Illustrationen
15
57 farbige Abbildungen, 15 s/w Abbildungen
XII, 314 p. 72 illus., 57 illus. in color.
Dateigröße
ISBN-13
978-1-4939-9195-2 (9781493991952)
DOI
10.1007/978-1-4939-9195-2
Schweitzer Klassifikation
