Modern Management of Cancer of the Rectum
is intended to provide a comprehensive overview of all aspects of rectal neoplasms. It addresses such topics as epidemiology, biology, screening and chemoprevention, the role of imaging in diagnosis, staging and prognosis, radiation therapy, medical and surgical treatment, as well as new modalities of therapy, including laparoscopy, and transanal endoscopic surgery. A greater understanding of prognostic factors, patterns of spread and natural history has occurred during the past decade; together with new diagnostic modalities this has led to significant changes in the management of patients with rectal cancer. This book will be invaluable for all those who treat rectal cancer.
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ISBN-13
978-1-4471-0331-8 (9781447103318)
DOI
10.1007/978-1-4471-0331-8
Schweitzer Klassifikation
1. Evolution of the Surgical Management of Rectal Cancer.- Perineal Approach.- Transanal Excision.- Transsacral Resection.- Abdominosacral Resection.- Abdominoperineal Resection.- Abdominoanal Approach.- Anterior Resection.- The Present.- References.- 2. Pathology and Staging.- Resection Specimen.- Total Mesorectal Excision.- Histological Features of Rectal Cancer and Their Prognostic Significance.- Surgical Resection Margins and Local Recurrence.- Staging of Rectal Cancer.- Role of Pathology in Assessing the Quality of Rectal Cancer Surgery.- Conclusions.- References.- 3. Genetics, Screening and Chemoprevention.- Screening.- Chemoprevention.- References.- 4. The Role of Imaging in the Diagnosis and Staging of Primary and Recurrent Rectal Cancer.- Diagnostic Imaging in the Staging of Primary Rectal Cancer.- Diagnostic Imaging in the Diagnosis and Staging of Recurrent Rectal Cancer.- Conclusions.- References.- 5. Neo-adjuvant Therapy.- Preoperative Therapy.- Is Adjuvant Therapy Necessary in Patients Undergoing a Total Mesorectal Resection?.- Investigational Approaches.- Summary.- References.- 6. Restorative Procedures.- Relevant Anatomy of the Rectum and Perirectal Tissues.- Surgical Options in Restorative Procedures.- Preoperative Evaluation and Patient Preparation.- Oncologic Principles in Rectal Surgery.- Technical Details.- Outcome After Low Anterior Resection Versus Abdominoperineal resection.- Laparoscopic Rectal Cancer Surgery.- Conclusions.- References.- 7. Abdominoperineal Resection.- Selection Factors for Abdominoperineal Resection.- Preoperative Preparation.- Operative Technique.- Intraoperative and Postoperative Complications.- Concluding Remarks.- References.- 8. Total Mesorectal Excision with Autonomic Nerve Preservation: "Optimized Surgery".- Rationaleof Total Mesorectal Excision and its Relationship to the Anatomy of Spread of Rectal Cancer.- Technique of Total Mesorectal Excision with Autonomic Nerve Preservation.- Outcome of Total Mesorectal Excision.- Morbidity of Total Mesorectal Excision.- Sexual and Urinary Function After Total Mesorectal Excision.- Extended Lateral Lymphadenectomy.- Role of the Colonic J-Pouch.- Role of Total Mesorectal Excision in Upper Rectal Cancer.- Summary.- References.- 9. Laparoscopic Resections for Large Bowel Malignancy: Laparoscopic Colectomy.- Laparoscopic Colectomy.- Summary.- Laparoscopic Rectal Cancer Surgery.- Conclusion.- References.- 10. Minimal Access Surgery for Rectal Cancer.- Preoperative Assessment.- Patient Selection for Local Treatment.- Therapeutic Modalities for Local Treatment.- Adjuvant Therapy after Local Treatment.- Salvage Treatment.- Palliative Local Surgery.- Summary.- References.- 11. Postoperative Adjuvant Combined Modality Therapy.- Postoperative Therapy.- Decreasing the Toxicity of Pelvic Radiation Therapy.- Is Adjuvant Therapy Necessary after Total Mesorectal Excision?.- Investigational Approaches.- Summary.- References.- 12. Follow-up After Potentially Curative Therapy for Rectal Cancer.- Background.- Methods of Recurrence Detection.- Recommendations.- Conclusions.- References.- 13. Surgical Approach to Locally Recurrent Disease.- Clinical Presentation.- Diagnostic Evaluation.- Preoperative Therapies.- Preoperative Planning.- Operative Strategy.- Intraoperative Radiation.- Results.- Extended Resection.- Future Directions.- References.- 14. Metastatic Rectal Cancer.- Surgery for Metastatic Rectal Cancer.- Chemotherapy Versus Best Supportive Care for Patients with Advanced Colorectal Cancer.- 5-Fluorouracil.- Chronomodulated Chemotherapy.- 5-Fluorouraciland Mitomycin C.- Oral Fluoropyrimidimes.- Irinotecan.- Raltitrexed.- Oxaliplatin.- Intra-Arterial Hepatic Chemotherapy for Isolated Liver Metastases.- Biological Therapy.- Conclusion.- References.- 15. Rare Histiotypes.- Carcinoid Tumors of the Rectum.- Lymphoma ofthe Rectum.- Anorectal Melanoma.- Neuroendocrine Carcinoma of the Rectum.- Vascular Lesions.- Squamous Cell and Adenosquamous Carcinoma of the Rectum.- Sarcoma of the Rectum.- References.- 16. Quality of Life and Palliative Care in Rectal Cancer Patients.- Quality of Life: Defining and Measurement Issues.- Quality of Life Studies.- Palliative Care in Rectal Cancer Patients.- Conclusions.- References.- 17. Costs of Rectal Cancer Patient Management.- Methods.- Conclusion.- References.
