Natural Products Targeting Clinically Relevant Enzymes

Name: Natural Products Targeting Clinically Relevant Enzymes
Brand: Wiley-VCH
Price: 142.99 EUR
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Paula B. Andrade Patricia Valentao David M. Pereira(Herausgeber*in)

Wiley-VCH (Verlag)

1. Auflage

Erschienen am 29. August 2017

XVIII, 330 Seiten

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Beschreibung

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PAULA B. ANDRADE is Associate Professor at the Faculty of Pharmacy of the University of Porto. As head of the Pharmacognosy lab, she also coordinates the natural products group of the REQUIMTE/LAQV, an institute active in Green Chemistry, and evaluates research projects for various international entities. Her research on bioactive substances originating from matrices of marine and terrestrial origin was published in more than 30 book chapters and more than 300 articles in international journals.

PATRICIA VALENTÃO obtained her PhD in Pharmaceutical Sciences at the University of Porto for work on pharmacognosy. She was appointed Assistant Professor at the Faculty of Pharmacy, University of Porto in 2007. Her research focuses on qualitative and quantitative metabolite profiling of terrestrial and marine natural matrices with the goal to reveal composition/activity relationships of these compounds in various clinically-relevant areas. Patricia Valentão is member of the REQUIMTE/LAQV Institute of Green Chemistry and editorial board member of the "EJournal of Chemistry". She (co)authored more than 30 book chapters and more than 250 articles in international journals.

DAVID M. PEREIRA obtained his PhD in Pharmaceutical Sciences at the University of Porto for work on phytochemistry and pharmacognosy. In 2014 he was appointed Assistant Professor at the Faculty of Pharmacy of the same university. David Pereira edited one book, contributed more than 20 book chapters and over 60 papers covering research areas of natural products, inflammation, drug discovery and analytical techniques. He also serves in the Editorial Board of several journals related to natural products and analytical techniques. He is appointed expert in the "Global Burden of Disease" program of the University of Washington, and reviewer/consultant in Biomedical Sciences for several European institutions.

Herausgeber*in

Paula B. Andrade

University of Porto, Portugal

Patricia Valentao

University of Porto, Portugal

David M. Pereira

University of Porto, Portugal

Inhalt

Natural products as enzyme inhibitors
Natural ACE inhibitors with antihypertensive properties
Hypoglycaemic effects of plants food constituents via inhibition of carbohydrate-hydrolysing enzymes: from chemistry to future applications.
Natural Product Inhibitors of Cyclooxygenase (COX) Enzymes: Current Status and Future Perspective
Natural Products Targeting Clinically Relevant Enzymes of Eicosanoid Biosynthesis implicated in inflammation and cancer
Natural inhibitors of mitochondrial respiratory chain: therapeutic and toxicological implications
Angiotensin-I-Converting enzyme (ACE-I) inhibitors from marine bio-resources
Refreshing the Marine-derived Chemotherapeutic Pipeline
Recent developments on the natural products and their derivatives targeting PfDHFR (Dihydrofolate reductase) and PfHSP (Heat sensitive protein)
Phospholipase A2 inhibitors of marine origin: a target for inflammation
Natural Plant-derived Acetylcholinesterase Inhibitors: Relevance for Alzheimer's disease
Molecular Targets of Clinically-Relevant Natural Products from Filamentous Marine Cyanobacteria
Natural inhibitors of beta-secretase
Anti-HIV natural products

List of Contributors

Catarina Andrade
REQUIMTE/LAQV Universidade do Porto
Laboratório de Farmacognosia Departamento de Química Faculdade de Farmácia
Rua de Jorge Viterbo Ferreira, Nº 228,
4050-213 Porto
Portugal

Paula B. Andrade
REQUIMTE/LAQV
Universidade do Porto
Laboratório de Farmacognosia Departamento de Química Faculdade de Farmácia
Rua de Jorge Viterbo Ferreira, Nº 228,
4050-213 Porto
Portugal

Anna Arola-Arnal
Universitat Rovira i Virgili
Biochemistry and Biotechnology Department
Marcel lí Domingo s/n
43007 Tarragona
Spain

Vasundhra Bhandari
University of Hyderabad
Department of Animal Biology
School of Life Sciences
Hyderabad
500046 Telangana
India

Anupam Bishayee
Larkin University
Department of Pharmaceutical Sciences
College of Pharmacy
Miami, FL 33169
USA

Marco Bonesi
University of Calabria
Department of Pharmacy
Health and Nutritional Sciences
Rende (CS)
Italy

Nady Braidy
UNSW Medicine
School of Psychiatry, NPI
Barker Street
Randwick
NSW 2031
Australia

Francisca I. Bravo
Universitat Rovira i Virgili
Biochemistry and Biotechnology Department
Marcel lí Domingo s/n
43007 Tarragona
Spain

Helen Chan
Genning Partners Company Limited
Causeway Bay; Institute of Medical Research Central; and Vita Green
Pharmaceutical (Hong Kong), Ltd. Tai Po, N.T.
Hong Kong
China

Chi Fai Cheung
The Chinese University of Hong Kong
School of Biomedical Sciences
Faculty of Medicine Shatin, N.T.,
Hong Kong
China

Ramesh Dasari
Texas State University
Department of Chemistry and Biochemistry
San Marcos TX 78666
USA

Shobha Ediga
University of Hyderabad
Department of Animal Biology
School of Life Sciences
Hyderabad
500046 Telangana
India

Wei-Shuo Fang
Institute of Materia Medica
Chinese Academy of Medical Science
Beijing 100050
China

Priyanka Voori Giri
University of Hyderabad
Department of Animal Biology
School of Life Sciences
Hyderabad
500046 Telangana
India

Nelson G. M. Gomes
REQUIMTE/LAQV
University of Porto
Laboratory of Pharmacognosy
Department of Chemistry
Faculty of Pharmacy
R. Jorge Viterbo Ferreira Nº.
2284050-313 Porto
Portugal

Na Guo
Institute of Materia Medica
Chinese Academy of Medical Science
Beijing 100050
China

Tharusha Jayasena
UNSW Medicine
School of Psychiatry, NPI
Barker Street
Randwick NSW 2031
Australia

Robert Kiss
Université Libre de Bruxelles
Campus de la Plaine
Laboratoire de Cancérologie et de Toxicologie
Expérimentale
Faculté de Pharmacie
CP205/1, Boulevard du Triomphe
1050 Brussels
Belgium

Alexander Kornienko
Texas State University
Department of Chemistry and Biochemistry
San Marcos TX 78666
USA

Naresh Kumar
University of Hyderabad
Department of Animal Biology
School of Life Sciences
Hyderabad
500046 Telangana
India

Vipan Kumar
Guru Nanak Dev University
Department of Chemistry
Grand Trunk Road
Amritsar 143005
India

Florence Lefranc
Université Libre de Bruxelles
Service de Neurochirurgie
Hôpital Erasme
808 Route de Lennik
1070 Brussels
Belgium

Monica R. Loizzo
University of Calabria
Department of Pharmacy Health and Nutritional Sciences Rende (CS)
Italy

Maria Margalef
Universitat Rovira i Virgili
Biochemistry and Biotechnology Department
Marcel lí Domingo s/n
43007 Tarragona
Spain

Begoña Muguerza
Universitat Rovira i Virgili
Biochemistry and Biotechnology Department
Marcel lí Domingo s/n
43007 Tarragona
Spain

Seyed M. Nabavi
Baqiyatallah University of Medical Sciences
Applied Biotechnology Research Center
Tehran
Iran

Charlene Cheuk Wing Ng
GKT School of Medicinal Education
King's College London SEI IUL
United Kingdom

Tzi Bun Ng
The Chinese University of Hong Kong
School of Biomedical Sciences
Faculty of Medicine Shatin, N.T.,
Hong Kong
China

Nuria de Pedro
Life Length
Parque Científico de Madrid
Faraday 7
Campus de Cantoblanco
28049 Madrid Spain

Fernando Peláez
CNIO - Spanish National Cancer Research Centre Biotechnology Programme
C/Melchor Fernández Almagro, 3
28029 Madrid
Spain

David M. Pereira
REQUIMTE/LAQV
Universidade do Porto
Laboratório de Farmacognosia Departamento de Química Faculdade de Farmácia
Rua de Jorge Viterbo Ferreira, Nº 228, 4050-213 Porto
Portugal

Renato B. Pereira
REQUIMTE/LAQV
University of Porto
Laboratory of Pharmacognosy
Department of Chemistry
Faculty of Pharmacy
R. Jorge Viterbo Ferreira Nº. 228
4050-313 Porto
Portugal

Anne Poljak
UNSW Medicine
School of Psychiatry, NPI
Barker Street
Randwick NSW 2031
Australia

Raghu Raj
Guru Nanak Dev University
Department of Chemistry
Grand Trunk Road
Amritsar 143005
India

Chintalapally V. Rao
University of Oklahoma
Center for Cancer Prevention
and Drug Development
Health Sciences Center
Oklahoma city, OKUSA

Luca Rastrelli
University of Salerno
Department of Pharmacy
Fisciano (SA)
Italy

Pallu Reddanna
University of Hyderabad
Department of Animal Biology
School of Life Sciences
Hyderabad
500046 Telangana
India

Gorla V. Reddy
University of Hyderabad
Department of Animal Biology
School of Life Sciences
Hyderabad
500046 Telangana
India

Perminder Sachdev
UNSW Medicine
School of Psychiatry, NPI
Barker Street
Randwick NSW 2031
Australia

Tânia Silva
REQUIMTE/LAQV
Universidade do Porto
Laboratório de Farmacognosia Departamento de Química Faculdade de Farmácia
Rua de Jorge Viterbo Ferreira Nº 228 4050-213 Porto
Portugal

Sandhya Singh
University of Hyderabad
Department of Animal Biology
School of Life Sciences
Hyderabad
500046 Telangana
India

Eduardo Sobarzo-Sánchez
University of Santiago de Compostela
Laboratory of Pharmaceutical Chemistry
Department of Organic Chemistry Faculty of Pharmacy 15782 Santiago de Compostela
Spain
and
Universidad Central de Chile
Instituto de Investigación e Innovación en Salud
Facultad de Ciencias de la...

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