Aortic Dissection: Simulation Tools for Disease Management and Understanding

Name: Aortic Dissection: Simulation Tools for Disease Management and Understanding
Brand: Springer
Price: 96.29 EUR
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Mona Alimohammadi(Autor*in)

Springer (Verlag)

Erschienen am 20. Januar 2018

XXIX, 179 Seiten

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978-3-319-56327-5 (ISBN)

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Inhalt

Intro
Supervisors' Foreword
Abstract
List of PublicationsJournal Publications1. Alimohammadi, M., Agu, O., Balabani, S. and D?az-Zuccarini, V. (2014), 'Development of a patient-specific tool to analyse aortic dissections: Assessment of mixed patient-specific flow and pressure boundary condition', Medical Engineering and Physics 36, 275-284.2. Alimohammadi, M., Bhattacharya-Ghosh, B., Seshadri, S., Penrose, J., Agu, O., Balabani, S. and D?az-Zuccarini, V. (2014), 'Evaluation of the hemodynamic effectiveness of aortic dissection trea
Journal Publications
Book Chapters
Conferences
Workshops Attended
Acknowledgements
Contents
Nomenclature
List of Figures
List of Tables
1 Introduction
1.1 Motivation and Background
1.1.1 Introduction to the Circulatory System
1.1.2 Aortic Dissection
1.2 Numerical Modelling of the Cardiovascular System
1.2.1 Background
1.2.2 Approaches to Modelling Aortic Dissection
1.2.3 Objectives of Aortic Dissection Modelling
1.3 Objectives of the Present Research
1.4 Outline of the Thesis
References
2 Computational Methods for Patient-Specific Modelling
2.1 Computational Fluid Dynamics
2.1.1 Governing Equations
2.1.2 Numerical Implementation
2.2 Building the Fluid Domain
2.2.1 Introduction to Clinical Imaging
2.2.2 3D Domain Extraction
2.2.3 Geometry
2.3 Meshing
2.4 Dynamic Boundary Conditions
2.4.1 Analogue Equations
2.4.2 Two-element Windkessel Model
2.4.3 Three-element Windkessel Model
2.4.4 Four-element Windkessel Models
2.4.5 Compound Windkessel Models
2.4.6 Parameters for Windkessel Models
2.4.7 Comparison of Zero-Pressure and Windkessel Boundary Conditions for Aortic Dissection
2.4.8 Comparison of Flow-Split and Windkessel Boundary Conditions for Aortic Dissection
2.5 Finite Element Modelling
2.5.1 Vessel Wall Reconstruction
2.5.2 Material Properties
References
3 Haemodynamics of a Dissected Aorta
3.1 Introduction
3.2 Methodology
3.2.1 Boundary Conditions and Data Assimilation Method
3.3 Results
3.3.1 Flow Characteristics
3.3.2 Pressure Distribution
3.3.3 Wall Shear Stress
3.4 Discussion
3.4.1 Limitations
3.5 Sensitivity of the Windkessel Parameters
3.6 Mesh Sensitivity
3.7 Effect of Turbulence Modelling
3.8 Conclusions
References
4 Effectiveness of Aortic Dissection Treatments via Virtual Stenting
4.1 Introduction
4.2 Methodology
4.2.1 Boundary Conditions
4.3 Results
4.3.1 Velocity and Flow Rates
4.3.2 Pressure
4.3.3 Kinetic Energy
4.3.4 Wall Shear Stress
4.4 Discussion
4.5 Mesh Sensitivity
4.6 Conclusion
References
5 Role of Vessel Wall Motion in Aortic Dissection
5.1 Introduction
5.2 Methods
5.2.1 Geometry
5.2.2 Boundary Conditions
5.3 Results
5.3.1 Wall Displacement
5.3.2 Cross-Sectional Area
5.3.3 Wall Stress
5.3.4 Velocity Distribution
5.3.5 Flow Distribution
5.3.6 Pressure Distribution
5.3.7 Proximal and Distal False Lumen
5.3.8 Wall Shear Stress
5.4 Mesh Sensitivity and Efficiency
5.5 Discussion
5.6 Conclusions
References
6 Conclusions and Future Work
6.1 Introduction
6.2 Main Contributions
6.3 Summary of Main Findings
6.4 Significance of this Study
6.5 Future Work
Appendix A Sample Mesh Images
Appendix B Detailed Mesh Sensitivity Analysis for Virtual-Stenting Simulations

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