Advances in Clinical Chemistry

Name: Advances in Clinical Chemistry
Brand: Academic Press
Price: 165.0 EUR
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Academic Press

Erschienen am 11. Oktober 2000

342 Seiten

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978-0-08-052230-2 (ISBN)

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Front Cover
Advances in Clinical Chemistry
Copyright Page
Contents
Contributors
Preface
Chapter 1. The Biochemistry of Aging
1. Introduction
2. Life Expectancy versus Maximum Life Span
3. Theories of Aging
4. Support for Free Radical Theory
5. Magnesium, Zinc, and Selenium.
6. Heat Shock Proteins
7. Age-Associated Diseases/Disorders
8. Summary
References
Chapter 2. Cystatin C-Properties and Use as Diagnostic Marker
1. Protease-Antiprotease Equilibria
2. Biological Roles of Papain-like Cysteine Proteases
3. The Cystatin Superfamily of Inhibitors of Papain-like Cysteine Proteases
4. The Human Cystatins
5. Identification of Target Enzymes for Cystatins
6. Distribution of Cystatins in Body Fluids
7. Additional Functions Attributed to Cystatin C
8. Previous Designations for Cystatin C
9. Structure of Human Cystatin C and Its Concentration in Body Fluids
10. Serum/Plasma Cystatin C as a Marker for Glomerular Filtration Rate (GFR)
11. Urine Cystatin C as a Marker for Proximal Tubular Damage
12. Cystatin C and Cerebral Hemorrhage
References
Chapter 3. The Role of Receptors In Prostate Cancer
1. Introduction
2. Androgen Receptors
3. Estrogen Receptors and Other Cytoplasmic/Nuclear Receptors
4. Growth Factor Receptors
5. Other Membrane Receptors
6. Conclusion
References
Chapter 4. Oxidative Modifications of Protein Structures
1. Sources of Reactive Oxygen Species
2. Oxidative Modifications of Protein Structures
3. Biological Effects of Protein Oxidation
4. Detection of Oxidatively Modified Proteins in a Clinical Laboratory
References
Chapter 5. Selected Markers of Bone Biochemistry
1. Introduction
2. Cytokines and Other Factors
3. Regulation of the Apoptosis of Osteoclasts
4. Hormones
5. Proinsulin, Insulin, Insulin-like Growth Factors (IGF), IGF-Binding Proteins, and Changes in Bone Metabolism in Diabetes Mellitus
6. Biochemical Markers of the Metabolism of Bone Tissue
References
Chapter 6. Laboratory Markers of Ovarian Function
1. Introduction
2. Age
3. Basal Hormone Levels
4. Function of the Pituitary-Ovarian Axis
5. Follicular Fluid
6. Granulosa Cells
7. Quality of Embryos
8. Hormone Levels after Embryo Transplant
9. Discussion and Conclusion
References
Index

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