Studienarbeit aus dem Jahr 2025 im Fachbereich Biologie - Krankheiten, Gesundheit, Ernährung, , Sprache: Deutsch, Abstract: Ambient air pollution has emerged as a major public health threat, contributing significantly to the global burden of non-communicable diseases, particularly cardiovascular disease (CVD). Despite growing epidemiological evidence, establishing a causal relationship remains complex due to the multifactorial nature of CVD. This paper applies Bradford Hill's criteria of causation to critically examine whether long-term exposure to ambient air pollutants-particularly fine particulate matter (PM2.5), nitrogen dioxide (NO2), and ozone (O3)-can be considered a causal factor in the development and progression of cardiovascular conditions such as coronary artery disease, stroke, and hypertension.
Findings from cohort studies, time-series analyses, and experimental models indicate strong and consistent associations between air pollution and cardiovascular outcomes. The biological plausibility is supported by mechanisms involving oxidative stress, systemic inflammation, endothelial dysfunction, and atherosclerosis. Evidence of temporality, dose-response relationships, and experimental reversibility further strengthens the case. While challenges such as exposure misclassification and socioeconomic confounding remain, the application of Hill's framework suggests that ambient air pollution is not merely associated with but likely contributes causally to cardiovascular disease.
Given the substantial and preventable health burden, this analysis underscores the urgent need for stricter air quality regulations and cross-sectoral policy interventions to reduce exposure and mitigate cardiovascular risk.
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978-3-389-14011-6 (9783389140116)
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Biography of Kingsley Adimabua:
Kingsley Adimabua is a dedicated and experienced Humanitarian and Development worker hailing from Abuja, Nigeria. With a career spanning 11 years, Kingsley has made significant contributions to various esteemed organizations within the field. His passion for making a positive impact on communities and his expertise in Monitoring and Evaluation (M&E) and Information and Knowledge Management have set him apart as a strong candidate.
Throughout his professional journey, Kingsley has had the privilege of working with reputable organizations such as Malaria Consortium, Christian Aid, Cuso International, Save the Children, Oxfam Novib, eHealth Africa, CBM International, and Palladium in Nigeria. His notable achievements include establishing a harmonized Post Distribution Monitoring system for a consortium of organizations involved in the Nigerian Joint Humanitarian Response and implementing effective Information and Knowledge management systems for Oxfam Novib's humanitarian response.
Kingsley's skill set extends beyond M&E and Information and Knowledge Management. He possesses expertise in establishing quality standards and internal quality assurance mechanisms and is proficient in statistical analysis using tools such as Excel, STATA, SPSS, Epi-Info, and MicroStrategy. Additionally, his excellent writing and presentation skills have been honed through his professional experience.
Passionate about helping people and driven by a desire to make a difference, Kingsley is a valuable asset to any team. He thrives on challenges, demonstrates adaptability, and possesses strong leadership qualities. Kingsley's unwavering dedication to humanitarian and development work, combined with his affinity for working with numbers and figures, make him a valuable addition to any organization.
In his pursuit of professional growth, Kingsley is eager to take on increased responsibilities and contribute to an organization's growth in a higher role. He is patient, adaptable, and committed to exceeding expectations. Kingsley's ultimate goal is to continue making a positive impact on communities and contribute to the growth and success of the organization he joins.
If given the opportunity, Kingsley would be delighted to discuss his qualifications further in an interview. For any inquiries or to schedule an interview, please feel free to contact him via email at greygoblings@gmail.com.
