In recent years, fine-needle aspiration cytology (FNAC) has become a widely accepted procedure in the diagnosis of bone lesions. Rapid progress in immunocytochemistry and molecular genetics has increased the role of FNAC in the investigation of primary bone lesions. The purpose of this book is to facilitate the cytological evaluation of FNA smears from skeletal lesions and to provide diagnostic criteria based on the combined evaluation of clinical data and radiographic and cytological features. The major aim is to thoroughly describe and illustrate the most common entities as well as the diagnostic use of ancillary techniques. A number of rare primary bone tumours/lesions are also illustrated. The selection of entities illustrated in this comprehensive manual is based mainly on experience with patients referred to the Musculoskeletal Centre in Lund, Sweden, which now comprises smear data from approximately 1000 skeletal tumours/lesions collected between 1966 and 2006. This publication will be a valuable resource for pathologists, cytopathologists, radiologists, oncologists and orthopaedic surgeons involved in the work-up and management of patients with bone lesions.
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Verlagsort
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Zielgruppe
Illustrationen
88 fig., 61 in color, 10 tab.
Gewicht
ISBN-13
978-3-8055-9214-7 (9783805592147)
Schweitzer Klassifikation
Preface; Epidemiology of Bone Tumours; Radiological Investigation of Bone Tumours; Tumour Type and Radiological Appearance; Other Investigations; Conclusion; Morphological Diagnosis of Bone Tumours; Biopsies; Fine Needle Aspiration; Ancillary Diagnostic Techniques; Diagnosis of Bone Tumours/Lesions; Diagnostic Accuracy Bone Lesion FNA; Pitfalls in Bone Tumour FNA; Complications of Bone Tumour FNA; Cytology of Normal Constituents in Bone Aspirates and of Reactive Changes; Normal Cells in Bone Aspirates; Reactive Changes; Cytological Features of Bone Tumours in FNA Smears I: Osteogenic Tumours; Osteid Osteoma and Osteoblastoma; Osteosarcoma; Case Report 1; Case Report 2; Cytological Features of Bone Tumours in FNA Smears II: Cartilaginous Tumours; Chondroma; Chondroblastoma; Chondromyxoid Fibroma; Chondrosarcoma; Dedifferentiated Chondrosarcoma; Clear-Cell Chondrosarcoma; Mesenchymal Chondrosarcoma; Case Report 3; Cytological Features of Bone Tumours in FNA Smears III: Ewing Family Tumours; The Ewing Family of Tumours; Case Report 4; Cytological Features of Bone Tumours in FNA Smears IV: Notochordal Tumours; Chordoma; Case Report 5; Cytological Features of Bone Tumours in FNA Smears V: Giant-Cell Lesions; Conventional Giant-Cell Tumour; Aneurysmal Bone Cyst; Giant-Cell Reparative Granuloma; Osteitis Fibrosa Cystica; Rare Targets for FNAC and Diagnostic Problems with Benign Tumours/Lesions with Variable Numbers of Osteoclast-Like Giant Cells; Rare Targets: Metaphyseal Fibrous Defect; Rare Targets: Fibrous Dysplasia; Rare Targets: Adamantinoma; Benign Bone Tumours/Lesions: Diagnostic Problems with Variable Numbers of Osteoclast-Like Giant Cells; Lymphohaematopoetic and Histiocytic Tumours; Solitary Plasmacytoma of Bone; Primary Lymphoma of Bone; Langerhans Cell Histiocytosis; Inflammatory Lesions; Non-Specific Osteomyelitis; Tuberculous Osteomyelitis; Bone Metastases; Metastatic Cancer; Case Report 6; Fine Needle Aspiration as the First Diagnostic Modality for Spinal and Sacral Lesions; References; Index.
