This book explains and demonstrates with real and simulated examples how whole-genome information can be used for predicting complex traits, with applications in animal, human, and plant genetics. After giving a brief introduction, the book covers linear models and dimensionality, plus regularized regressions. It then progresses to the genomic best linear unbiased predictor, the Bayesian alphabet, reproducing Kernel Hiblert spaces regressions, penalized neural networks, and re-sampling methods. Lastly, it covers whole genome regression and population stratification.
Reihe
Sprache
Verlagsort
Verlagsgruppe
Zielgruppe
Für höhere Schule und Studium
Illustrationen
20 s/w Abbildungen
20 Illustrations, black and white
Maße
Höhe: 234 mm
Breite: 156 mm
ISBN-13
978-1-4822-5374-0 (9781482253740)
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Schweitzer Klassifikation
Autor*in
University of Wisconsin-Madison, USA
Introduction. A Brief History of Quantitative Genetics. Complex Traits, Interactions, and Challenges to Prediction. Linear Models and the Curse of Dimensionality. Regularized Regressions. The Genomic Best Linear Unbiased Predictor. The Bayesian Alphabet. Reproducing Kernel Hiblert Spaces Regressions. Penalized Neural Networks. Re-sampling Methods. Whole Genome Regression and Population Stratification. Appendices.