Bipolar Disorder: From Neuroscience to Treatment

Preface.- The Neurobiology of Bipolar Disorder.- Pre-clinical studies and Animal Models.- Genetics in Bipolar.- Mitochondrial modulators for bipolar disorder: A paradigm for drug development.- Intracellular Signaling Cascades.- Circadian Rhythms and Sleep.- Neuroendocrine System in Bipolar.- Neuroanatomic and Functional Neuroimaging Findings.- Structural and Functional Aspects of Neuroprogression in BD.- Inflammation as a Mechanism of Neuroprogression.- Neurocognition in Bipolar.- The kindling/sensitization model and Early Life Stress.- Early Life Stress in Bipolar.- New pharmacological Interventions.