The volume presents a survey of the research by Kurt Wuethrich and his associates during the period 1965 to 1994. A selection of reprints of original papers on the use of NMR spectroscopy in structural biology is supplemented with an introduction, which outlines the foundations and the historical development of the use of NMR spectroscopy for the determination of three-dimensional structures of biological macromolecules in solution. The original papers are presented in groups highlighting protein structure determination by NMR, studies of dynamic properties and hydration of biological macromolecules, and practical applications of the NMR methodology in fields such as enzymology, transcriptional regulation, immunosuppression and protein folding.
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978-981-02-2384-7 (9789810223847)
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Schweitzer Klassifikation
Herausgeber*in
The Scripps Research Inst, Usa & Eth Zurich, Switzerland
NMR and structural biology; the avenue to three-dimensional protein structure determination in solution; establishing credibility for NMR structures of proteins; evolution of NMR structure determination with biological macromolecules 1985-94; selected NMR structure determination; conformational equilibria and internal mobility in proteins and in solution; hydration of proteins and nucleic acids in solution; protein folding.
