Humanization of Antibodies (Olivier Léger and José W Saldanha); Selection and Screening of Antibody Phage Display Libraries (David R Buckler, Darren Schofield, Daniel J Sexton, David Lowe and Tristan J Vaughan); Affinity Maturation Approaches for Antibody Lead Optimization (David Lowe, Trevor Wilkinson and Tristan J Vaughan); Transgenic Mice Rearranging Human Antibodies (Sean Stevens); Isotype Selection and Fc Engineering: Design and Construction of Fit-for-Purpose Therapeutic Antibodies (William R Strohl); Antibody Expression from Bacteria to Transgenic Animals (Paul Stephens and Berni M Sweeney); Current Trends in Antibody Purification and Lead Selection (Jie Chen and Andrew Nixon); Design and Application of Immunoconjugates for Cancer Therapy (Sherif El Sheikh, Hans-Georg Lerchen, Beate Müller-Tiemann and Jörg Willuda); Dual-Targeting Bispecific Antibodies as New Therapeutic Modalities for Cancer (Zhenping Zhu); Antibody Fragments and Alternate Protein Scaffolds (Lioudmila Tchistiakova, William J J Finlay, Stephane Olland, Helen Dooley and Davinder Gill).