Prevention. Prevention of mental, neurological, and psychological disorders: report by the Director-General. Relationship between treatment and prevention policies. Biological Treatments. Critical questions in clinical psychopharmacology. Biological treatments other than drugs (electroconvulsive therapy, brain surgery, insulin therapy, and phototherapy). Psychological Treatments. Evaluation of psychodynamic psychotherapy. Cognitive therapy. Behavior therapy. The benefits of psychotherapy. Psychosocial Treatments. Psychosocial interventions. Procedures used in rehabilitation. Influence of Culture on Treatment. Traditional medicine relevant to psychiatry. Cultural aspects of treatment: conceptual, methodological, and clinical issues and directions. Quality of Care and Care of Quality. Rational treatment in psychiatry: perspectives on psychiatric treatment by level of care. Quality assurance in mental health care. Conclusions: cure, relieve, and comfort.