Introduction - mechanisms in the life sciences versus creationist fundamentalism; population genetics, alleles and TIMA; on the nature of the theory of evolution; TIMA part 1 - TIMA as a paradigm for the evolution; TIMA part 2 - TIMA-based directed evolutionary adaptation; a theory of animal development - genetic control theory of developmental events; the wiring-in of neural nets revisited; on the likely nature of plant morphogenesis.