Fiber Toxicology

The known commercial uses of new mineral-fibre substitutes and non-asbestiform synthetics presents a potentially great health risk because most materials have not been tested for pathogenicity - "Fiber Toxicology" was written to help prevent a repeat of the asbestos dilemma. It examines the lessons learned from the toxicological study of asbestos and provides a framework for new toxicological studies on non-asbestos fibers. This book also introduces new state-of-the-art concepts and methods for evaluating the toxicology of various fibre-types on different pulmonary systems. It covers topics from the molecular biology to cell biology (in vitro) and from intraperitoneal to inhalation models. It also examines some of the most important controversies in fibre toxicology: "in vitro" versus "in vivo" and alternative methods of exposure (intraperitoneal) to physiological methods (inhalation). Finally, the proactive angle of this text is further enhanced with a chapter on carbon fibre toxicology - the only available lucid discussion of this emerging field.
 
The known commercial uses of new mineral-fibre substitutes and non-asbestiform synthetics presents a potentially great health risk because most materials have not been tested for pathogenicity - "Fiber Toxicology" was written to help prevent a repeat of the asbestos dilemma. It examines the lessons learned from the toxicological study of asbestos and provides a framework for new toxicological studies on non-asbestos fibers. This book also introduces new state-of-the-art concepts and methods for evaluating the toxicology of various fibre-types on different pulmonary systems. It covers topics from the molecular biology to cell biology (in vitro) and from intraperitoneal to inhalation models. It also examines some of the most important controversies in fibre toxicology: "in vitro" versus "in vivo" and alternative methods of exposure (intraperitoneal) to physiological methods (inhalation). Finally, the proactive angle of this text is further enhanced with a chapter on carbon fibre toxicology - the only available lucid discussion of this emerging field.