Gastrin

This volume is a comprehensive reference on the important gastrointestinal hormone gastrin. Leading investigators examine the molecular biology of gastrin and its major receptor; the physiology of gastrin as a hormone regulating gastric secretion and cell growth; the role of gastrin in peptic ulcer disease, endocrine hyperplasia, and gastric carcinoid tumour formation; and the potential of gastrin to act as a growth-promoting agent in colon cancer and small cell lung carcinoma. Important research findings presented included a description of the primary amino acid structure of the gastrin receptor and a study of the histamine-releasing activity of gastrin. Clinical issues addressed include the effects and potential side effects of drugs that eliminate gastric acid secretion; the differential diagnosis and significance of hypergastrinemia (including hypergastrinemia in Helicobacter pylori gastritis); and the diagnosis and management of gastrinomas.
 
This volume is a comprehensive reference on the important gastrointestinal hormone gastrin. Leading investigators examine the molecular biology of gastrin and its major receptor; the physiology of gastrin as a hormone regulating gastric secretion and cell growth; the role of gastrin in peptic ulcer disease, endocrine hyperplasia, and gastric carcinoid tumour formation; and the potential of gastrin to act as a growth-promoting agent in colon cancer and small cell lung carcinoma. Important research findings presented included a description of the primary amino acid structure of the gastrin receptor and a study of the histamine-releasing activity of gastrin. Clinical issues addressed include the effects and potential side effects of drugs that eliminate gastric acid secretion; the differential diagnosis and significance of hypergastrinemia (including hypergastrinemia in Helicobacter pylori gastritis); and the diagnosis and management of gastrinomas.