This volume represents the sum of contributions by the leading experts in the field, both in basic sciences and clinics, with the aim of reactivating attention towards a phenomenon which is fundamental in the context of human pain. The book helps the reader to understand the mechanisms behind the occurrence and tranferral of pain to superficial structures, and represents a statement of the present state of knowledge in this complex field.
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Elsevier Science & Technology
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Für höhere Schule und Studium
Für Beruf und Forschung
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ISBN-13
978-0-444-89631-5 (9780444896315)
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Schweitzer Klassifikation
Part 1 Pathophysiological mechanisms: neurophysiological mechanisms of referred pain and hyperalgesia; mechanisms of cutaneous and subcutaneous hyperalgesia; spinal mechanisms of muscle pain and hyperalgesia; pathophysiology of referred pain and hyperalgesia from viscera; spinal mechanisms of referred pain; brainstem mechanisms of referred pain and hyperalgesia in the orofacial and temporomandibular region; possible role of cortical and subcortical structures in the pathology of referred visceral pain and hyperalgesia; spinal visceral afferents, sympathetic nervous system and referred pain. Part 2 Experimental models: modeling modeling visceral pain; muscular hyperalgesia of renal/ureteral origin; the role of capsaicin-sensitive afferents in the genesis of vesical pain and inflammation; behavioural, electrophysiological and pharmacological studies of primary and secondary distant hyperalgesia in rats with moderate ligation of one sciatic nerve; neurophysiological and neuropharmacological studies on arthritic pain; fos-like immunoreactivity in the rat spinal cord during the development of polyarthritism - pharmacological investigations; integrated complex responses following tonic pain; experimental referred pain and hyperalgesia from muscles in humans. Part 3 Clinical aspects: the historical development of the concepts of hyperalgesia and referred pain; pathophysiology and clinical aspects of cardiac pain; gynecological and obstetrical pain; visceral heterotopical allodynia and hyperalgesia unmask the hidden dimension of nociceptive disorder in migraine; painful polyneuropathic sensory syndromes. Part 4 Therapeutic approach: effects of neural blockade on referred pain, hyperalgesia and allodynia; electrical stimulation for the treatment of referred pain; referred pain in cancer patients - effects of percutaneous cervical cordotomy; non-steroidal anti-inflammatory drugs and pain; hyperalgesia - modulation by opiates of the spinal and peripheral sensitizing processes; psychotropic drugs and referred pain. (Part Contents).
