Part 1 General perspectives: aging as a stage in the life cycle; demographic, comparative and differential aging; aging and disease; theories of aging. Part 2 Molecular and cellular aging: degenerative changes in cells and cell death; anzymatic changes in aging; oxygen radical generation and protective systems; aging of the immune system. Part 3 Systemic and organic aging: aging of the nervous system, functional changes; aging of the nervous system, sensory changes; aging of the hypothalmo-pituitary-adrenal system; aging of the female reproductive system, the menopause; aging of the male reproductive system; the thyroid and basal metabolism; the pancreas and glucose metabolism; aging of the cardiovascular metabolism - atherosclerosis; aging of the cardiovascular system - lipoproteins; the lung; the kidney; gastrointestinal system and liver; aging of the musculoskeletal system and heart; the skin, connective tissue and aging. Part 4 Prevention and rehabilitation: drug management and pharmacokinetics in the elderly; effects of nutrition on aging; physical medicine and rehabilitation; an agenda for healthful aging.
