Free radicals and human disease - trick or treat?; oxygen free radical involvement in cerebral ischemia/reperfusion injury; oxygen radicals and ageing; free radicals in rheumatoid arthritis - redox regulation of gene transcription and proteolytic tissue destruction; implication of reactive oxygen metabolites in inflammatory bowel disease; interleukin-1, neutrophils and oxidants in acute lung injury; free radicals and critical care medicine; human immunodeficiency virus-1 tat protein and oxidant/antioxidant balance; role of reactive oxygen species in multistage carcinogenesis.