Channelopathies in Heart Disease

Introduction.- Part 1: (Dys)function of cardiac ion channels. Cardiac sodium channel (dys)function and inherited arrhythmia syndromes.- Potassium channels in the heart.- Voltage-gated calcium channels and their roles in cardiac electrophysiology.- HCN channels and cardiac pacemaking.- Dysregulation of ionic homeostasis: relevance for cardiac arrhythmias.- Part 2: Cardiac channelopathies: clinical and genetic findings. Long and short QT syndromes.- Brugada syndrome: current perspectives.- Sinus node disease and cardiac conduction disease.- Catecholaminergic polymorphic ventricular tachycardia.- Idiopathic ventricular fibrillation and early repolarization.- Atrial fibrillation.- Genetic testing for inheritable cardiac channelopathies.- Part 3: Research into cardiac channelopathies: new avenues. Novel imaging techniques in cardiac ion channel research.- Transgenic animal models of cardiac channelopathies - benefits and limitations.- Induced pluripotent stem cell-derived cardiomyocytes: towards personalized therapeutic strategies?.