Molecular and Immune Mechanisms in the Pathogenesis of Cutaneous Leishmanias

This book is about the molecular and immune mechanisms of pathogenesis in cutaneous leishmaniasis. It introduces the reader to the cutaneous leishmaniasis model of invasion and defence against a unicellular parasite. Different views of the parasite and the disease are outlined through the text: biochemistry and ultrastructure, taxonomy of the parasite, the experimental model, the Th1 and Th2 response, humoral aspects and vaccination.