Part 1 Animal models for research on ageing: comparative perspectives on phenotypic plasticity in the SAM mouse strains and other animals, C.E. Finch; senescence accelerated mouse (SAM); a novel murine model of ageing, T. Takeda et al. Part 2 Topics in SAM research: murine senile amyloidosis and accelerated senescence, H. Naiki; molecular genetic studies on SAM, K. Higuchi. Part 3 Neuroscience in ageing and SAM research: characteristics of memory and behavioral disorders in SAMP8 mice, M. Miyamoto; neurochemical studies on ageing in SAM brain, Y. Nomura et al. Part 4 Cellular, molecular, biochemical and physiological aspects of senescence: molecular biological study of the AKR-type thymoma in SAM, L. Mio et al; serum lipid peroxide level of the senescence-accelerated mouse, S. Komura et al. Part 5 Immunology and senescence: genetic control of defective helper T cell activity in in vitro antibody responses in short-lived SAM mice, K. Hanada et al; abnormalities of B cells and dendritic cells in SAMP1 mice, H. Haruna et al. Part 6 Periodontal tissue and joints: cytokins in bone marrow of SAMP6/Ta, K. Yoh et al; metal concentrations in liver, kidney and femur of SAMP6/Ta, N. Koizumi and R. Ninomiya. Part 7 Sensory organs: morphological study on cataractous lens of senescence accelerated mouse (SAM), H. Nishimoto et al; age-related hearing impairment in senescence-accelerated mouse (SAM), Y. Saitoh et al. Part 8 Lung, reproductive organs and amyloidosis: a novel model of ageing lung, Y. Fukuchi et al; quantitative studies on spermatogenesis in the senescence accelerated mouse, H. Miyamoto et al. Part 9 Neurobiology I - development and degeneration: electrophysiological and morphological studies of SAMP10 frontal cortex neurons, H. Nakanishi et al; changes with age in the mineral status in brain of female SAMP1 and SAMR1, A. Morita et al. Part 10 Neurobiology II - cell biology, excitable membrane and synaptic transmission: relationship between radiation and acceleration of ageing, M. Iseki et al; ultrastructural study of PAS-positive granular structures (PGS) in brains of SAMP8, M. Irino et al. Part 11 Neurobiology III - neural basis of behavior: deficit of short-term memory in SAMP8, A. Ohta et al; studies on genetic aspects of impaired learning and memory in SAMP8 mice, J.F. Flood and J.E. Morley. Part 12 Amelioration of impaired learning ability: FGF facilitation of learning and memory and protection from memory loss in senescence accelerated mice, Y. Oomura et al; effects of cholinomimetics on the disturbance of passive avoidance response in senescence-accelerated mice, M. Suzuki et al. (Part Contents).
