Comprehensive reference reviewing how thermodynamic principles underpin the design of drug products and their applications
Written in an easy-to-read and understand style, Thermodynamics for Drug Product Design offers an abundance of real-life drug product design examples, applications, personal anecdotes, and solved problems that contextualize thermodynamic principles for the drug product design scientist. Advanced undergraduate and beginning graduate students will learn to apply thermodynamic principles to create robust drug products and to predict, prevent, analyze, and evaluate the root cause of product failures. Professionals engaged in drug product design will find this book to be a rich and easy to use reference guide.
The first two chapters address some key basics of data reporting and analysis, math, and thermodynamic properties using simple and accessible language. These chapters also help readers understand fundamental underlying definitions and physical relationships required to use thermodynamic laws in the design of drug products. In later chapters, the book focuses on six industrial pharmacy relevant thermodynamic topics: the laws of thermodynamics, Gibbs free energy, equilibrium, drug solubility equilibrium, surface thermodynamics, and adsorption phenomena.
Thermodynamics for Drug Product Design features chapters including:
Data Reporting and Analysis
Underlying Thermodynamic Physical Property Relationships and Definitions
The Laws of Thermodynamics
Gibbs Free Energy
Equilibrium
Drug Solubility Equilibrium
Surface Thermodynamics
Adsorption Phenomena
What others say:
"...comprehensive, rigorous, and logically organized ...the explanations flow effortlessly from the page..."
-BRUNO HANCOCK, PhD, FAAPS, Editor, JPharmSci
"...has a unique style of communicating complex scientific issues..."
-KEN MORRIS, PhD, FAAPS, Professor Emeritus, Founding Director Lachman Institute
"...unusual wide range of subjects...unusual for detail..."
-DALE ERIC WURSTER, PhD, FAAPS, Professor Emeritus, 2019 AAPS President
Sprache
Verlagsort
Zielgruppe
Für Beruf und Forschung
Für höhere Schule und Studium
Produkt-Hinweis
Fadenheftung
Gewebe-Einband
ISBN-13
978-1-119-85109-7 (9781119851097)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Klassifikation
William Craig Stagner, RPh, MS, PhD is Professor Emeritus and formerly Director of the Campbell University Pharmaceutical Sciences Institute and Director of the Center for Analysis of Pharmaceutical Biomaterials at Campbell University College of Pharmacy & Health Sciences at Buies Creek, NC. Prior to joining the faculty, he founded the Pharmaceutics Department at the Glaxo Research Institute in Research Triangle Park, NC. Among his publications are co-authoring both editions of the Wiley title Integrated Pharmaceutics: Applied Preformulation, Product Design, and Regulatory Science.
