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This volume aims provides timely reviews with special focus on the clinical aspects of brain molecular imaging. The chapters reflect the interdisciplinary nature of the field detailing, glutamate receptor imaging, tau and amyloid imaging, glucose metabolism, opioid receptor, dopamine receptor imaging, brain metabolite measurements by 1H-MRS, and analytical methods using artificial intelligence, which have become extremely important in recent years. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting-edge and comprehensive, Molecular Imaging for Brain Diseases provides methods to navigate this complex field and inspire a deeper appreciation for the brain's molecular underpinnings.
Recent progress in NMDA glutamate receptor imaging.- Manipulation and imaging of plasticity of the glutamate synapse for brain diseases in living human.- Advanced Tau imaging in Alzheimer's disease and other types of dementia.- PET visualization of brain tau accumulations secondary to various CNS injuries: Chronic traumatic encephalopathy (CTE) and organophosphorus poisoning.- Amyloid PET imaging and quantification of amyloid deposition.- 18F-FDG PET for Neurodegenerative Diseases: Principles and Progress.- Opioid receptor and advanced nuclear imaging in epilepsy.- High-affinity state of dopamine D2/3 receptors in schizophrenia: A dual-radioligand approach.- Finding the Fire: Mapping Brain Temperature Elevations as a Surrogate of Focal Neuroinflammation.- Magnetic resonance spectroscopy and its application of mild traumatic brain injury.- Glutamate and proton MR Spectroscopy in Schizophrenia.- Artificial Intelligence for Molecular Brain Imaging.