Human lymphomas have become of great interest in recent years, because of a dramatic increase in understanding of the different lymphoid cell types giving rise to these tumours, and because modern treatment, involving surgery, radiotherapy, chemotherapy and marrow transplantation, have improved the overall prognosis. Lymphomas also provide insights into the role of oncogenes in cell physiology. Continued improvement in the management of non-Hodgkin's lymphomas is dependent on close collaboration between pathologists, basic scientists and oncologists. The authorship of this book includes clinicians and pathologists and their partnership reflects their professional collaboration. When dealing with genetics, histological methods, normal and abnormal lymph nodes, nodal and extra nodal non-Hodgkin's lymphomas, and modern therapeutics, the authors stress clinical and pathological correlations. An important feature is the emphasis on non-Hodgkin's lymphomas in tissues other than the lymph node.
Sprache
Verlagsort
Zielgruppe
Für höhere Schule und Studium
Für Beruf und Forschung
Illustrationen
319 photographs, 100 tables and figures
Maße
Höhe: 260 mm
Breite: 190 mm
Gewicht
ISBN-13
978-1-874545-07-1 (9781874545071)
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Schweitzer Klassifikation
Part 1 Lymphomagenesis: Lymphocyte differentiation; Adult T-cell leukaemia/Lymphoma - a model of retrovirus-induced lymphomagenesis; Burkitt's lymphoma and Epstein-Barr virus-associated lymphoid malignancies - models for lymphomagenesis; T(14;18) translocation. Part 2 Methods: Histological and immunohistochemical methods; Genotype. Part 3 Nodal Non-Hodgkin's Lymphomas: The normal lymph node - structure and function; Histological classification; Staging of NHLs; Analytical study of the different subtypes of NHLs - clinical, histological and immunohistochemical aspects; NHLs in childhood; NHLs associated with HIV infection. Part 4 Extra-Nodal Non-Hodgkin's lymphomas: Malignant lymphomas of mucosa-associated lymphoid tissues; Primary gastrointestinal NHLs; Pathology of gastro-intestinal NHLs; Cutaneous lymphomas; NHLs of the Mediastinum; NHLs of the lung; Bone marrow involvement; Blood involvement in chronic (mature) B & T lymphoproliferative syndromes; Liver involvement; Spleen involvement; Extra-cranial head-and-neck NHLs; Central nervous system involvement; NHLs of bone; Urogenital localizations. Part 5 Treatment of Non-Hodgkin's Lymphomas: Methodology and problems in the comparison of results; Treatment of lowgrade NHLs; The role of radiation therapy; Treatment of aggressive lymphomas (intermediate and highgrade); Intensive chemoradiotherapy and bone-marrow transplantation; Salvage therapy after failure; Treatment of NHLs in childhood.
