This completely updated, second edition of the Essentials has been expanded by seven chapters to include such hot topics in genomics as DNA chip fabrication, yeast two hybrid analysis, tools for gene expression studies, metabolic networks/systems biology and genes and patents. The first section introduces the domains of application for genomics and bioinformatics, such as sequencing and the comparative sequence analysis of model organisms, investigating genetically influenced diseases and the development of new active substances. There then follows an overview of current topics central to DNA technologies, proteomics and bioinformatics. The whole is rounded off by four chapters on the ethical, legal and social aspects of genome research.
Auflage
Sprache
Verlagsort
Zielgruppe
Editions-Typ
Maße
Höhe: 240 mm
Breite: 170 mm
ISBN-13
978-3-527-31030-2 (9783527310302)
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Schweitzer Klassifikation
Introduction; Application Domains - Genome Projects of Model Organisms - The Human Genome Project - Genetic Diseases - Pharmaceutical Bioinformatics and Drug Discovery - Agri-Food and Genomics - Environmental Genomics; DNA Technologies - Genomic Mapping and Positional Cloning, wiht Emphasis on Plant Science - Sequencing Technology - DNA Chip Fabrication - A DNA Microarray Application Strategy for Research Laboratories; Protein Technologies - Two-Dimensional Gel Electrophoresis and Mass Spectrometry - Proteome Analysis by Capillary Electrophoresis - Yeast-Two Hybrid Analyses; Bioinformatics - Using the Molecular Biology Data - Tools for DNA Technologies - Tools for Protein Technologies - Tools for Gene Expression Studies - Structure Information - Genomic Data Representation through Images - Interaction Databases - Metabolic Networks; Ethical Legal and Social Issues - Ethical Aspects of Genome Research and Banking - Genes and Patents - Genomics and the Church - Genomics - Five Years from Now