Part 1 Structure and function of cytochrome P-450: structure, purification, properties - cytochrome P-450 in respiratory tract, cytochrome P-450 and steroidal hormone synthesis, cytochrome P-450 and fatty-acid-metabolism, cytochrome P-450 and the brain, cytochrome P-450 in plants and fungi; interactions with ligands, lipids, proteins - ligand binding, interactions with the membrane and membrane proteins. Part 2 Dynamics of structure and function. Part 3 Models and calculations: models of structure and function; quantitations. Part 4 Genetics, regulation and evolution: cytochrome P-450I-family; cytochrome P-450II-family; alcohol-inducible cytochrome P-450 subfamily; cytochrome P-450III-family; cytochrome P-450IV-family; steroid-hydroxylases; yeast-cytochrome P-450. Part 5 Environmental aspects of cytochrome P-450: aquatic environment; metabolism, inhibition, toxicity; induction by xenobiotics; regulation (induction) by endogenous effectors.