Over the last three decades, knowledge on the molecular biology of human cancers has vastly expanded. A host of genes and proteins involved in cancer development and progression have been defined and many mechanisms at the molecular, cellular and even tissue level have been, at least partly, elucidated. Insights have also been gained into the molecular mechanisms underlying carcinogenesis by chemical, physical, and biological agents and into inherited susceptibility to cancer.
More than ever, cancer research is now an interdisciplinary effort which requires a basic knowledge of commonly used terms, facts, issues, and concepts. The aim of this book is to provide advanced students and practitioners of different disciplines with this basis, bridging the gap between standard textbooks of molecular biology, pathology, and oncology on the one hand and the specialized cancer literature on the other.
Rezensionen / Stimmen
From the reviews:
"Although Molecular Biology of Human Cancers is intended as a text for a graduate-level course, it is even more valuable for researchers like me, as a thoughtful encapsulation of the important areas of contemporary cancer research. . the book is well designed as a text. The prose is clear, the numerous diagrams and tables are helpful . . is unique in both coverage and perspective. Overall, I know of no other single source that provides a thoughtful view of more areas of molecular cancer research." (Joseph Locker, Angiogenesis, Vol. 7, 2004)
"This is a detailed and comprehensive review of the molecular aspects of cancer aetiology and development in man. It is aimed at advanced students and trainees in cancer-related disciplines and thus at a rather broad-spectrum audience. . Overall, this is an interesting and informative book, which would be helpful to students wishing to have some in-depth knowledge of cancer genetics, and an overview of general concepts in this field . ." (Shirley Hodgson, Human Genetics, Vol. 123, 2008)
Auflage
Sprache
Verlagsort
Zielgruppe
Für höhere Schule und Studium
Für Beruf und Forschung
Professional/practitioner
Illustrationen
Maße
Höhe: 23.2 cm
Breite: 15.6 cm
Gewicht
ISBN-13
978-1-4020-3185-4 (9781402031854)
DOI
10.1007/978-1-4020-3186-1
Schweitzer Klassifikation
Part I.
1 An Introduction to Human Cancers.
2 Tumor Genetics.
3 DNA Damage and DNA Repair.
4 Oncogenes.
5 Tumor Suppressor Genes.
6 Cancer Pathways.
7 Apoptosis and Replicative Senescence in Cancer.
8 Cancer Epigenetics.
9 Invasion and metastasis.
Part II.
10 Leukemias and Lymphomas.
11 Wilms Tumor (nephroblastoma).
12 Cancers of the skin.
13 Colon Cancer.
14 Bladder Cancer.
15 Renal Cell Carcinoma.
16 Liver Cancer.
17 Stomach Cancer.
18 Breast Cancer.
19 Prostate Cancer. Part III.
20 Cancer Prevention.
22 Cancer Therapy.
