This new edition covers recent advances in understanding immunological and inflammatory responses in the nervous system, research driven by the potential to use knowledge of the molecules and mechanisms involved to intervene in, and arrest, neurodegenerative disease processes.
Immune and Inflammatory Responses in the Nervous System covers developmental aspects of immune/inflammatory responses in the CNS, basic aspects of glial function, as well as inflammatory mediators, their mechanisms of action, clinical importance and sites of infection. There is also coverage of the major diseases of the CNS, including stroke, brain injury, multiple sclerosis and Alzheimer's disease. Throughout, the focus is on the underlying basic neuroscience, clinical relevance and the potential for therapeutic interventions.
This will be an invaluable aid to understanding and improving the diagnosis of neuroimmune diseases and determining therapeutic measures.
The contributors are all leading experts in the field and the content will be of interest to neuroscientists, neurologists, neuropathologists, neurosurgeons and immunologists.
Rezensionen / Stimmen
This well-structured and balanced account of our current knowledge of immune and inflammatory aspects of CNS disorders will appeal to researchers and clinicians alike. * Journal of Neurology * . . . provides a clear, concise, informative, and most importantly, readable, collection of up-to-date essays on various aspects of inflammation in the CNS. Because of the diversity of the contributor's view points, I think that it would provide a good introduction for those unfamiliar with inflammation or for those unfamiliar with the special problems relating to the nervous system. * Brain *
Reihe
Auflage
Sprache
Verlagsort
Zielgruppe
Editions-Typ
Illustrationen
numerous figures and halftones
Maße
Höhe: 248 mm
Breite: 172 mm
Dicke: 16 mm
Gewicht
ISBN-13
978-0-19-850980-6 (9780198509806)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Klassifikation
Herausgeber*in
, School of Biological Sciences, University of Manchester, UK
, School of Biological Sciences, University of Manchester UK
1. Developmental influences on inflammation in the brain ; 2. Imaging inflammation in the brain ; 3. Astrocytic networks and brain injury ; 4. Blood-brain barrier and perivascular cells ; 5. CNS responses to peripheral insults ; 6. Inflammatory events in focal cerebral ischaemia ; 7. Cytokines and neurodegeneration ; 8. Inflammatory responses to traumatic brain injury: an overview for the millennium ; 9. Inflammatory demyelination and axonopathy in the CNS ; 10. CNS immune reactions in Alzheimer's disease ; 11. Transplantation of neuronal and non-neuronal cells into the brain