Prof. Dr. Dr. h. c. Klaus Joachim Zülch. In Memoriam.- Pathophysiology I (Cell Volume Regulation, Methods).- Effects of Lactacidosis on Volume and Viability of Glial Cells.- Mechanisms Underlying Glutamate-induced Swelling of Astrocytes in Primary Culture.- The Mechanical Filtration Coefficient (Lp) of the Cell Membrane of Cultured Glioma Cells (C6).- Swelling of Astroglia in vitro and the Effect of Arginine Vasopressin and Atrial Natriuretic Peptide.- Brain Interstitial Composition During Acute Hyponatremia.- Do the Skull and Dura Exert Influence on Brain Volume Regulation Following Hypo- and Hyperosmolar Fluid Treatment?.- In vivo Measurement of Intra- and Extracellular Space of Brain Tissue by Electrical Impedance Method.- Intracellular pH Regulation of Normal Rat Brain: 31P-MRS Study.- Measurement of Canine Cerebral Oedema Using Time Domain Reflectometry.- A New Mapping Study of Superoxide Free Radicals, Vascular Permeability and Energy Metabolism in Central Nervous System.- Measurement of Brain Tissue Density Using Pycnometry.- Pathophysiology II (Methods, Mediators).- Experimental Studies for Use of Magnetic Resonance in Brain Water Measurements.- MR Studies of Brain Oedema in the Developing Animal.- Passage of DMP Across a Disrupted BBB in the Context of Antibody-mediated MR Imaging of Brain Metastases.- Continuous Monitoring of Blood-Brain Barrier Opening to Cr51-EDTA by Microdialysis Following Probe Injury.- Effects of Antineutrophil Serum (ANS) on Posttraumatic Brain Oedema in Rats.- The Effect of Immunosuppression with Whole Body and Regional Irradiation on the Development of Cerebral Oedema in a Rat Model of Intracerebral Haemorrhage.- Effect of Stimulation of Leukocyte Chemotaxis by fMLP on White Blood Cell Behaviour in the Microcirculation of Rat Brain.- Leukotriene Production by Human Glia.- The Role of Arachidonic Acid and Oxygen Radicals on Cerebromicrovascular Endothelial Permeability.- Possible Mechanism of Vasogenic Brain Oedema Induced by Arachidonic Acid.- Effects of the Arachidonate Lipoxygenase Inhibitor BW755C on Traumatic and Peritumoural Brain Oedema.- The Contribution of Secondary Mediators to the Etiology and Pathophysiology of Brain Oedema: Studies Using a Feline Infusion Oedema Model.- Comparative Effects of Direct and Indirect Hydroxyl Radical Scavengers on Traumatic Brain Oedema.- Pathophysiology III (Formation, Resolution).- The Effects of Cerebral Haemodynamics on the Progression of Cold-Induced Oedema.- Cryogenic Brain Oedema: Loss of Cerebrovascular Autoregulation as a Cause of Intracranial Hypertension. Implications for Treatment.- An Electron Microscopic and Electron Probe Study of the Microcirculation in Cold-Induced Oedema.- Accumulation of Oedema Fluid in Deep White Matter After Cerebral Cold Injury.- A Microstructural Study of Oedema Resolution.- Routed Protein Migration After Protein Extravasation and Water Leakage Caused by Cold Injury.- Immunocytochemical Studies of Oedema Protein Clearance in the Rat.- Pathophysiology IV (Treatment).- Effects of Anaesthetic Agents on Cerebral Blood Flow and Brain Oedema from a Focal Lesion in Rabbit Brain.- Dose- and Time-dependent Effects of Dexamethasone on Rat Brain Following Cold-injury Oedema.- The Effect of Various Steroid Treatment Regimens on Cold-induced Brain Swelling.- Steroid and Hyperosmotic Diuretic Effects on the Early Phase of Experimental Vasogenic Oedema.- The Ambivalent Effects of Early and Late Administration of Mannitol in Cold-induced Brain Oedema.- Magnetic Resonance Study of Brain Oedema Induced by Cold Injury - Changes in Relaxation Times Before and After the Administration of Glycerol.- Transient Effect of Mannitol on Cerebral Blood Flow Following Brain Injury.- Effects of Atrial Natriuretic Peptide on Brain Oedema: The Change of Water, Sodium, and Potassium Contents in the Brain.- Tumour and Brain Oedema (I).- In vivo Measurement of Brain Water by MRI.- 1H-NMR Studies on Water Structures in the Rat Brain Tissues with Cerebral Tumour or Ischaemia.- Magnetic Resonance Imaging and Regional Biochemical Analysis of Experimental Brain Tumours in Cats.- Magnetic Resonance Studies in Human Brain Oedema Following Administration of Hyperosmotic Agents.- MRI Contrast Enhancement by MnTPPS of Experimental Brain Tumours in Rats.- Human Malignant Gliomas Secrete a Factor that Increases Brain Capillary Permeability: Role in Peritumoural Brain Oedema.- Selective Opening of the Blood-Tumour Barrier by Intracarotid Infusion of Leukotriene C4.- Oxygen Free Radicals in the Genesis of Peritumoural Brain Oedema in Experimental Malignant Brain Tumours.- Effect of Recombinant Human Lipocortin I on Brain Oedema in a Rat Glioma Model.- Tumour and Brain Oedema (II).- Formation and Resolution of White Matter Oedema in Various Types of Brain Tumours.- Fluid Flow Rates in Human Peritumoural Oedema.- The Finite Element Analysis of Brain Oedema Associated with Intracranial Meningiomas.- The Effect of the Aminosteroid U-78517G on Peritumoural Brain Oedema.- Novel 21-aminosteroids Prevent Tumour Associated Neurological Dysfunction.- Therapeutic Effects of Topical Dexamethasone on Experimental Brain Tumours and Peritumoural Brain Oedema.- Evaluation of Glucose Transport in Malignant Glioma by PET.- Cerebral Blood Flow and Rheologic Alterations by Hyperosmolar Therapy in Patients with Brain Oedema.- Ischaemia and Brain Oedema I (Global Ischaemia).- Restoration of Energy Metabolism and Resolution of Oedema Following Profound Ischaemia.- Selective, Delayed Increase in Transfer Constants for Cerebrovascular Permeation of Blood-Borne 3H-Sucrose Following Forebrain Ischaemia in the Rat.- Electrical Impedance, rCBF, Survival and Histology in Mongolian Gerbils with Forebrain Ischaemia.- Excitatory Amino Acid Receptors, Oxidoreductive Processes and Brain Oedema Following Transient Ischaemia in Gerbils.- Cellular Swelling During Cerebral Ischaemia Demonstrated by Microdialysis in vivo: Preliminary Data Indicating the Role of Excitatory Amino Acids.- Role of Neuroexcitation in Development of Blood-Brain Barrier and Oedematous Changes Following Cerebral Ischaemia and Traumatic Brain Injury.- Inducible Ornithine Decarboxylase Expression in Brain Subject to Vasogenic Oedema After Transient Ischaemia: Relationship to C-fos Gene Expression.- Ischaemic Brain Oedema and Xanthine-Xanthine Oxidase System.- The Role of Endothelial Second Messenger's-Generating System in the Pathogenesis of Brain Oedema.- Effect of Glutamate and Its Antagonist on Shift of Water from Extra- to Intracellular Space After Cerebral Ischaemia.- Effect of Atrial Natriuretic Peptide on Ischaemic Brain Oedema.- Suppression of Water Shift into Intracellular Space by TA-3090 (Calcium Entry Blocker) Measured with NMR.- Ischemia and Brain Oedema II (Focal Ischemia).- Early Detection of Ischemic Injury: Comparison of Spectroscopy, Diffusion-, T2-, and Magnetic Susceptibility-Weighted MRI in Cats.- Diffusion-Weighted MR Imaging and T2-Weighted MR Imaging in Acute Cerebral Ischaemia: Comparison and Correlation with Histopathology.- Blood-Brain Barrier Disruption Following CPR in Piglets.- Relationship Between Cerebral Blood Flow and Blood-Brain Barrier Permeability of Sodium and Albumin in Cerebral Infarcts of Rats.- Extravasation of Albumin in Ischaemic Brain Oedema.- Pathophysiological Studies in the Rat Cerebral Embolization Model: Measurement of Epidural Pressure and Evaluation of Tissue pH and ATP.- Determiners of Fatal Reperfusion Brain Oedema.- Ischaemia and Brain Oedema III.- Brain Oedema and Intracranial Pressure in Superior Sagittal Sinus Balloon Occlusion. An Experimental Study in Pigs.- Early Pathomorphological Changes and Intracranial Volume-Pressure: Relations Following the Experimental Saggital Sinus Occlusion.- Liposome-entrapped Superoxide Dismutase Ameliorates Infarct Volume in Focal Cerebral Ischaemia.- Effects of Ebselen (PZ 51) on Ischaemic Brain Oedema After Focal Ischaemia in Cats.- Post-ischaemic Treatment with the Prostacycline Analogue TTC-909 Reduces Ischaemic Brain Injury.- Attenuation of Glutamate-induced Neuronal Swelling and Toxicity in Transgenic Mice Overexpressing Human CuZn-Superoxide Dismutase.- Effects of Atrial Natriuretic Peptide on Ischaemic Brain Oedema Evaluated by the Proton Magnetic Resonance Method.- Nimodipine Attenuates Both Ischaemia-induced Brain Oedema and Mortality in a Rat Novel Transient Middle Cerebral Artery Occlusion Model.- MR Evaluation of Calcium Entry Blockers with Putative Cerebroprotective Effects in Acute Cerebral Ischaemia.- Effect of Steroid Therapy on Ischaemic Brain Oedema and Blood to Brain Sodium Transport.- Dexamethasone Does not Influence Infarct Size but Causes Haemorrhage in Baboons with Cerebral Infarcts.- Trauma and Brain Oedema (I).- Brain Oedema in Experimental Closed Head Injury in the Rat.- Development of Regional Cerebral Oedema After Lateral Fluid-Percussion Brain Injury in the Rat.- Survival and Fibre Outgrowth of Neuronal Cells Transplanted into Brain Areas Associated with Interstitial Oedema.- Effect of Murine Recombinant Interleukin-1 on Brain Oedema in the Rat.- Early Cellular Swelling in Experimental Traumatic Brain Injury: A Phenomenon Mediated by Excitatory Amino Acids.- Changes in Extracellular Glutamate Concentration After Acute Subdural Haematoma in the Rat - Evidence for an "Excitotoxic" Mechanism?.- Ischaemic Brain Damage Associated with Tissue Hypermetabolism in Acute Subdural Haematoma: Reduction by a Glutamate Antagonist.- Autoradiographic Patterns of Brain Interstitial Fluid Flow After Collagenase-induced Haemorrhage in Rat.- Analysis of MRI and SPECT in Patients with Acute Head Injury.- The Time Course of Vasogenic Oedema After Focal Human Head Injury - Evidence from SPECT Mapping of Blood Brain Barrier Defects.- Intracerebral Haematoma: Aetiology and Haematoma Volume Determine the Amount and Progression of Brain Oedema.- Trauma and Brain Oedema (II).- Gadolinium-DTPA Enhanced Magnetic Resonance Imaging in Human Head Injury.- Blood-Brain Barrier Damage in Traumatic Brain Contusions.- Large and Small "Holes" in the Brain: Reversible or Irreversible Changes in Head Injury.- Hemispheric CBF-Alterations in the Time Course of Focal and Diffuse Brain Injury.- Correlations Between Brain Oedema Volume on CT and CSF Dynamics in Severely Head Injured Patients.- Oedema Fluid Formation Within Contused Brain Tissue as a Cause of Medically Uncontrollable Elevation of Intracranial Pressure: The Role of Surgical Therapy.- Magnetic Resonance Imaging and Neurobehavioural Outcome in Traumatic Brain Injury.- The Effect of Nimodipine on Outcome After Head Injury: A Prospective Randomized Control Trial.- Effect of THAM on Brain Oedema in Experimental Brain Injury.- A Comparative Analysis of THAM (Tris-buffer) in Traumatic Brain Oedema.- A Comparison of the Cerebral and Haemodynamic Effects of Mannitol and Hypertonic Saline in an Animal Model of Brain Injury.- Traumatic Brain Swelling and Operative Decompression: A Prospective Investigation.- The Novel 21-aminosteroid U-74006F Attenuates Cerebral Oedema and Improves Survival After Brain Injury in the Rat.- The Increase in Local Cerebral Glucose Utilization Following Fluid Percussion Brain Injury is Prevented with Kynurenic Acid and is Associated with an Increase in Calcium.- Various Disease Processes and Brain Oedema I (Hypertension, Hyperammonemia, Hydrocephalus).- Presence of Transendothelial Channels in Cerebral Endothelium in Chronic Hypertension.- Blood-Brain Barrier Disruption Caused by Impairment of Cerebral Autoregulation During Chronic Cerebral Vasospasm in Primates.- Effect of L-arginine on Haemoglobin-induced Inhibition of Endothelium-dependent Relaxation of Isolated Cerebral Arteries.- Cerebrovascular Permeability in Acute Hypertension: Effect of Flunarizine.- Glutamine Synthetase Inhibition Prevents Cerebral Oedema During Hyperammonemia.- Hydrocephalic Oedema in Normal-pressure Hydrocephalus.- Local Cerebral Blood Flow and Glucose Metabolism in Hydrostatic Brain Oedema.- Changes in Free Water Content and Energy Metabolism of the Brain in Experimental Hydrocephalus.- Venous and Cerebrospinal Fluid Outflow in Patients with Brain Swelling and Oedema.- Various Disease Processes and Brain Oedema II (Pseudotumour, Irradiation, Infection, Stress).- Brain Water Accumulation in Pseudotumour Cerebri Demonstrated by MR-imaging of Brain Water Self-Diffusion.- Pseudotumour Cerebri-neurosurgical Considerations.- Clinical Evaluation and Long-Term Follow-up in 16 Patients with Pseudotumour Cerebri.- Polyamine Accumulation and Vasogenic Oedema in the Genesis of Late Delayed Radiation Injury of the Central Nervous System (CNS).- Dynamics of Tracer Distribution in Radiation Induced Brain Oedema in Rats.- Superoxide Dismutase Inhibits Brain Oedema Formation in Experimental Pneumococcal Meningitis.- Perifocal Brain Oedema in Experimental Brain Abscess in Rats.- Brain Oedema and Cellular Changes Induced by Acute Heat Stress in Young Rats.- Brain Oedema, Mass Effects, CBF.- Automated Time-averaged Analysis of Craniospinal Compliance.- Changes in Epidural Pulse Pressure in Brain Oedema Following Experimental Focal Ischaemia.- Hemodynamic Effects of Decompressive Craniectomy in Cold Induced Brain Oedema.- Blood Flow and Metabolism in Vasogenic Oedema.- Effect of Mannitol on Intracranial Pressure-Volume Status and Cerebral Haemodynamics in Brain Oedema.- Effect of Gammahydroxybutyrate on Intracranial Pressure, Mean Systemic Arterial Pressure and Cerebral Perfusion Pressure in Experimentally Induced Brain Oedema of the Rat.- Evaluation of Oedema Spreading and Intracranial Volume Reserve Using CT Image Numerical Analysis.- Quantitative Analysis of CT Visualized Periventricular and Perifocal Brain Oedema by Means of CSF Dynamics Infusion Test.- VPF and Interstitial Fluid Pressure in Brain Oedema.- Author Index.- Listed in Current Contents.